两个新的人类FGF基因FGF11和FGF12的染色体定位
Chromosomal mapping of two novel human FGF genes, FGF11 and FGF12.
作者信息
Verdier A S, Mattei M G, Lovec H, Hartung H, Goldfarb M, Birnbaum D, Coulier F
机构信息
U 119 INSERM, Marseille, France.
出版信息
Genomics. 1997 Feb 15;40(1):151-4. doi: 10.1006/geno.1996.4492.
PMID:9070933
Abstract
The fibroblast growth factor (FGF) family comprises to date 12 members, which are involved in various physiological processes throughout embryogenesis and adult life. Two novel members of the family have been identified recently (FGF11 and FGF12). Using in situ hybridization on metaphasic chromosomes, we have been able to assign FGF11 to band p12-p13 of human chromosome 17 and FGF12 to band q28 of human chromosome 3.
摘要
成纤维细胞生长因子（FGF）家族迄今包含12个成员，它们参与胚胎发育和成年期的各种生理过程。该家族最近鉴定出两个新成员（FGF11和FGF12）。通过对中期染色体进行原位杂交，我们已将FGF11定位于人类染色体17的p12 - p13带，将FGF12定位于人类染色体3的q28带。
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