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The three human trefoil genes TFF1, TFF2, and TFF3 are located within a region of 55 kb on chromosome 21q22.3.

作者信息

Seib T, Blin N, Hilgert K, Seifert M, Theisinger B, Engel M, Dooley S, Zang K D, Welter C

机构信息

Department of Human Genetics, University of Saarland, Homburg, Germany.

出版信息

Genomics. 1997 Feb 15;40(1):200-2. doi: 10.1006/geno.1996.4511.

DOI:10.1006/geno.1996.4511
PMID:9070946
Abstract
摘要

相似文献

1
The three human trefoil genes TFF1, TFF2, and TFF3 are located within a region of 55 kb on chromosome 21q22.3.三种人类三叶因子基因TFF1、TFF2和TFF3位于21号染色体q22.3区域55kb的范围内。
Genomics. 1997 Feb 15;40(1):200-2. doi: 10.1006/geno.1996.4511.
2
Human trefoil peptides: genomic structure in 21q22.3 and coordinated expression.人三叶肽：21q22.3的基因组结构及协同表达
Eur J Hum Genet. 1996;4(6):308-15. doi: 10.1159/000472224.
3
Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues.三叶肽（TFF1、TFF2和TFF3）在胃癌、肠化生及非肿瘤性胃组织中的表达
J Pathol. 2002 Aug;197(5):582-8. doi: 10.1002/path.1147.
4
Hepatocyte nuclear factor 3 (winged helix domain) activates trefoil factor gene TFF1 through a binding motif adjacent to the TATAA box.肝细胞核因子3（翼状螺旋结构域）通过与TATAA盒相邻的结合基序激活三叶因子基因TFF1。
DNA Cell Biol. 1999 Feb;18(2):157-64. doi: 10.1089/104454999315547.
5
A third P-domain peptide gene (TFF3), human intestinal trefoil factor, maps to 21q22.3.
Cytogenet Cell Genet. 1996;72(4):299-302. doi: 10.1159/000134208.
6
Expression of TFF1, TFF2 and TFF3 in gastric cancer.三叶因子1、三叶因子2和三叶因子3在胃癌中的表达。
Int J Oncol. 2002 Sep;21(3):655-9.
7
A PvuII polymorphism detected by a cDNA clone of the gene encoding the human spasmolytic protein protein (SML1 gene), one of three members of the trefoil peptide gene family clustered on chromosome 21q22.3.
Clin Genet. 1997 Oct;52(4):247-8. doi: 10.1111/j.1399-0004.1997.tb02556.x.
8
Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2.转录因子GATA-6激活胃保护三叶因子基因TFF1和TFF2的表达。
Biochim Biophys Acta. 2000 Feb 29;1490(3):324-32. doi: 10.1016/s0167-4781(00)00013-0.
9
TFF peptides in the human efferent tear ducts.人泪液输出管中的三叶因子家族肽
Invest Ophthalmol Vis Sci. 2002 Nov;43(11):3359-64.
10
The gene encoding human intestinal trefoil factor (TFF3) is located on chromosome 21q22.3 clustered with other members of the trefoil peptide family.
Genomics. 1996 Mar 1;32(2):281-4. doi: 10.1006/geno.1996.0117.

引用本文的文献

1
Trefoil Factor Peptides and Gastrointestinal Function.三叶因子肽与胃肠功能
Annu Rev Physiol. 2017 Feb 10;79:357-380. doi: 10.1146/annurev-physiol-021115-105447. Epub 2016 Dec 15.
2
Trefoil factor-3 expression in human colon cancer liver metastasis.三叶因子-3在人结肠癌肝转移中的表达
Clin Exp Metastasis. 2009;26(2):143-51. doi: 10.1007/s10585-008-9224-9. Epub 2008 Nov 2.
3
Trefoil factor family-3 is associated with aggressive behavior of colon cancer cells.三叶因子家族3与结肠癌细胞的侵袭性行为相关。
Clin Exp Metastasis. 2005;22(2):157-65. doi: 10.1007/s10585-005-6615-z.
4
Altered mucin expression in the gastrointestinal tract: a review.胃肠道中黏蛋白表达的改变：综述
J Cell Mol Med. 2001 Jul-Sep;5(3):327-51. doi: 10.1111/j.1582-4934.2001.tb00169.x.
5
Mucin gene expression in intestinal epithelial cells in Crohn's disease.克罗恩病中肠上皮细胞的黏蛋白基因表达
Gut. 2001 Oct;49(4):544-51. doi: 10.1136/gut.49.4.544.
6
Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa.黏蛋白和三叶肽在溃疡相关细胞谱系及胃肠道黏膜中的协同定位。
Gut. 2000 Dec;47(6):792-800. doi: 10.1136/gut.47.6.792.
7
The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach.人类双结构域三叶因子蛋白TFF2在胃中进行体内糖基化。
Gut. 2000 Apr;46(4):454-9. doi: 10.1136/gut.46.4.454.