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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Higashino H, Simeonova K, Lambev I, Markov M, Suzuki A

Department of Pharmacology, Kinki University School of Medicine, Osaka-Sayama, Japan.

Clin Exp Pharmacol Physiol Suppl. 1995 Dec;22(1):S292-3. doi: 10.1111/j.1440-1681.1995.tb02923.x.

The effect of environmental temperature on the indirect measurement of rat blood pressure and heart rate was investigated with special reference to the tail arterial blood flow in both strains of SHRSP and WKY. 2. Very good correlations (r > 0.82, P < 0.05; t-test, 10 d.f.) were observed between the two values of systolic blood pressure or heart rate measured by a direct and an indirect method at environmental temperatures between 26 and 38 degrees C in SHRSP, and 34 and 38 degrees C in WKY, respectively. 3. When the temperature was elevated by 10 degrees C from 25 degrees C to 35 degrees C, the regional blood flow in the tail artery increased by 52-69%, sufficient to detect a blood flow increase by the indirect method. 4. These data showed that the best way to measure the accurate blood pressure and heart rate in both strains of SHRSP and WKY by the indirect volume-oscillometric method was to hold the rats at 34-36 degrees C for 5 min.

研究了环境温度对大鼠血压和心率间接测量的影响，并特别参考了SHRSP和WKY两个品系大鼠的尾动脉血流情况。2. 在SHRSP品系中，环境温度在26至38摄氏度之间，以及在WKY品系中，环境温度在34至38摄氏度之间时，通过直接法和间接法测量的收缩压或心率的两个值之间观察到非常好的相关性（r>0.82，P<0.05；t检验，自由度为10）。3. 当温度从25摄氏度升高10摄氏度至35摄氏度时，尾动脉的局部血流量增加了52-69%，足以通过间接法检测到血流量的增加。4. 这些数据表明，通过间接容积示波法在SHRSP和WKY两个品系中准确测量血压和心率的最佳方法是将大鼠置于34-36摄氏度下5分钟。

Higashino H, Simeonova K, Lambev I, Markov M, Suzuki A

Department of Pharmacology, Kinki University School of Medicine, Osaka-Sayama, Japan.

Clin Exp Pharmacol Physiol Suppl. 1995 Dec;22(1):S292-3. doi: 10.1111/j.1440-1681.1995.tb02923.x.

The effect of environmental temperature on the indirect measurement of rat blood pressure and heart rate was investigated with special reference to the tail arterial blood flow in both strains of SHRSP and WKY. 2. Very good correlations (r > 0.82, P < 0.05; t-test, 10 d.f.) were observed between the two values of systolic blood pressure or heart rate measured by a direct and an indirect method at environmental temperatures between 26 and 38 degrees C in SHRSP, and 34 and 38 degrees C in WKY, respectively. 3. When the temperature was elevated by 10 degrees C from 25 degrees C to 35 degrees C, the regional blood flow in the tail artery increased by 52-69%, sufficient to detect a blood flow increase by the indirect method. 4. These data showed that the best way to measure the accurate blood pressure and heart rate in both strains of SHRSP and WKY by the indirect volume-oscillometric method was to hold the rats at 34-36 degrees C for 5 min.

研究了环境温度对大鼠血压和心率间接测量的影响，并特别参考了SHRSP和WKY两个品系大鼠的尾动脉血流情况。2. 在SHRSP品系中，环境温度在26至38摄氏度之间，以及在WKY品系中，环境温度在34至38摄氏度之间时，通过直接法和间接法测量的收缩压或心率的两个值之间观察到非常好的相关性（r>0.82，P<0.05；t检验，自由度为10）。3. 当温度从25摄氏度升高10摄氏度至35摄氏度时，尾动脉的局部血流量增加了52-69%，足以通过间接法检测到血流量的增加。4. 这些数据表明，通过间接容积示波法在SHRSP和WKY两个品系中准确测量血压和心率的最佳方法是将大鼠置于34-36摄氏度下5分钟。