Comer S W, Robbins A L, Staiff D C
Arch Environ Contam Toxicol. 1977;6(1):103-10. doi: 10.1007/BF02097753.
Pesticide workers usually contaminate their cigarettes with less than 100 microgram per cigarette by handling them, but in some instances such contamination has been found to be over 200 microgram. To obtain values for potential exposure resulting from smoking contaminated filter tip and nonfilter cigarettes, from 10 to 200 microgram of parathion was applied to the cigarette surface area found to be most often contaminated by hands. This was followed in two separate experiments by simulated smoking using a special apparatus to determine (1) passage of toxic material through cigarettes in mainstream smoke, (2) amount found in sidestream smoke, (3) amount trapped in the filter or equivalent butt end, and (4) amount recovered in ashes. The amount of parathion passing through cigarettes as a potential for inhalation exposure ranged up to 28% of dosing levels. No paraoxon or S-ethyl parathion was detected. Although there was an indication that slightly more pesticide was recovered from filters than from equivalent butt ends, the amount recovered in mainstream smoke of filter type cigarettes was not significantly lower than for nonfilter cigarettes. Location of contamination on a cigarette had minimal effect on the amount found in mainstream smoke.
农药工人在处理香烟时，通常每支香烟被污染的农药量不到100微克，但在某些情况下，发现这种污染量超过200微克。为了获取因吸食被污染的过滤嘴香烟和非过滤嘴香烟而产生的潜在暴露值，将10至200微克对硫磷涂覆在发现最常被手部污染的香烟表面积上。在两个独立实验中，随后使用特殊装置进行模拟吸烟，以确定：（1）有毒物质在主流烟雾中通过香烟的情况；（2）侧流烟雾中的含量；（3）被困在过滤嘴或等效烟头中的量；（4）在烟灰中回收的量。作为吸入暴露潜在源的通过香烟的对硫磷量高达给药水平的28%。未检测到对氧磷或S-乙基对硫磷。尽管有迹象表明从过滤嘴回收的农药比从等效烟头中回收的略多，但过滤嘴型香烟主流烟雾中回收的量并不显著低于非过滤嘴香烟。香烟上污染的位置对主流烟雾中的含量影响极小。
