Carnahan H, Aguilar O, Malla A, Norman R
Department of Kinesiology, University of Waterloo, Ontario, Canada.
Schizophr Res. 1997 Feb 28;23(3):213-21. doi: 10.1016/s0920-9964(96)00106-5.
The purpose of this study was to examine whether individuals with schizophrenia demonstrate slowing in movement planning (reaction time), or in movement execution (movement time and velocity), in comparison to normals. Twelve schizophrenic and 12 control right-handed males performed aiming movements with a mouse (controlled by either the left or right hand) on a graphics tablet towards targets of differing sizes and distances appearing on a computer screen. Results showed that, for reaction time, the controls were faster than the schizophrenics and the latter had a left hand advantage for movement preparation while the controls showed no such differences. For movement time, no group differences were found. However, as expected, movement times were shorter (i.e., movements were faster) to the large, and near targets. These results support Fitts' law (Fitts, 1954) which describes a relationship where aiming movement time decreases as target distance decreases, and target size increases. We provide evidence here for a movement planning deficit in schizophrenic patients with no decrement in movement execution compared to controls.
本研究的目的是检验与正常人相比，精神分裂症患者在运动计划（反应时间）或运动执行（运动时间和速度）方面是否表现出迟缓。12名精神分裂症患者和12名对照组成的右利手男性，在图形输入板上用鼠标（由左手或右手控制）向电脑屏幕上出现的不同大小和距离的目标进行瞄准动作。结果显示，在反应时间方面，对照组比精神分裂症患者更快，且精神分裂症患者在运动准备时有左手优势，而对照组则没有这种差异。在运动时间方面，未发现组间差异。然而，正如预期的那样，向大的、近的目标移动时运动时间更短（即动作更快）。这些结果支持了菲茨定律（菲茨，1954年），该定律描述了一种关系，即随着目标距离减小和目标大小增加，瞄准运动时间会减少。我们在此提供证据表明，与对照组相比，精神分裂症患者存在运动计划缺陷，但运动执行没有下降。
