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Enzymatic conversion of benzo(a)pyrene phenols, dihydrodiols and quinones to sulfate conjugates.

作者信息

Nemoto N, Takayama S, Gelboin H V

出版信息

Biochem Pharmacol. 1977 Oct 1;26(19):1825-9. doi: 10.1016/0006-2952(77)90356-2.

DOI:10.1016/0006-2952(77)90356-2
PMID:907722
Abstract
摘要

相似文献

1
Enzymatic conversion of benzo(a)pyrene phenols, dihydrodiols and quinones to sulfate conjugates.苯并(a)芘酚、二氢二醇和醌向硫酸酯共轭物的酶促转化。
Biochem Pharmacol. 1977 Oct 1;26(19):1825-9. doi: 10.1016/0006-2952(77)90356-2.
2
The in vitro oxidative metabolism of benzo(a)pyrene in human liver measured by different assays.通过不同检测方法测定人肝脏中苯并(a)芘的体外氧化代谢。
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Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to benzo(a)pyrene and to 7,8- and 9,10-dihydrobenzo(a)pyrene.芳香多环烃的环氧衍生物。与苯并(a)芘以及7,8-和9,10-二氢苯并(a)芘相关的环氧化物的制备与代谢。
Biochem J. 1972 Jun;128(2):265-77. doi: 10.1042/bj1280265.
4
K-region and non-K-region metabolism of benzo(a)pyrene by rat liver microsomes.大鼠肝微粒体对苯并(a)芘的K区和非K区代谢
Cancer Res. 1973 Aug;33(8):1937-44.
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Effects of inducers and epoxide hydrase on the metabolism of benzo(a)pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography.诱导剂和环氧化物水解酶对肝脏微粒体及重组系统中苯并(a)芘代谢的影响：高压液相色谱分析
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4356-60. doi: 10.1073/pnas.71.11.4356.
6
Radical cations as precursors in the metabolic formation of quinones from benzo[a]pyrene and 6-fluorobenzo[a]pyrene. Fluoro substitution as a probe for one-electron oxidation in aromatic substrates.
Biochem Pharmacol. 1988 Jun 1;37(11):2173-82. doi: 10.1016/0006-2952(88)90578-3.
7
Enzymatic conjugation of benzo (a) pyrene oxides, phenols and dihydrodiols with UDP-glucuronic acid.
Biochem Pharmacol. 1976 May 15;25(10):1221-6. doi: 10.1016/0006-2952(76)90373-7.
8
Mutagenicity and cytotoxicity of benzo(a)pyrene arene oxides, phenols, quinones, and dihydrodiols in bacterial and mammalian cells.苯并(a)芘芳烃氧化物、酚类、醌类和二氢二醇在细菌和哺乳动物细胞中的致突变性和细胞毒性。
Cancer Res. 1976 Sep;36(9 pt.1):3350-7.
9
Kinetic analysis of the metabolism of benzo(a)pyrene to phenols, dihydrodiols, and quinones by high-pressure chromatography compared to analysis by aryl hydrocarbon hydroxylase assay, and the effect of enzyme induction.通过高压色谱法对苯并(a)芘代谢为酚类、二氢二醇和醌类的动力学分析与通过芳烃羟化酶测定法的分析比较，以及酶诱导的影响。
Cancer Res. 1975 Dec;35(12):3642-50.
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Demonstration of microsomal oxygenation of the benzo ring of 6-nitrobenzo[a]pyrene by thin-layer chromatography.通过薄层色谱法证明6-硝基苯并[a]芘苯环的微粒体氧合作用。
J Chromatogr. 1984 May 18;291:231-9. doi: 10.1016/s0021-9673(00)95024-6.

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Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells.Cu/Zn-超氧化物歧化酶和/或过氧化氢酶的过表达通过上调小鼠内皮细胞芳烃受体加速苯并(a)芘解毒。
Free Radic Biol Med. 2009 Oct 15;47(8):1221-9. doi: 10.1016/j.freeradbiomed.2009.08.001. Epub 2009 Aug 7.