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Enzymatic conjugation of benzo (a) pyrene oxides, phenols and dihydrodiols with UDP-glucuronic acid.

作者信息

Nemoto N, Gelboin H V

出版信息

Biochem Pharmacol. 1976 May 15;25(10):1221-6. doi: 10.1016/0006-2952(76)90373-7.

DOI:10.1016/0006-2952(76)90373-7
PMID:938546
Abstract
摘要

相似文献

1
Enzymatic conjugation of benzo (a) pyrene oxides, phenols and dihydrodiols with UDP-glucuronic acid.
Biochem Pharmacol. 1976 May 15;25(10):1221-6. doi: 10.1016/0006-2952(76)90373-7.
2
Modification of benzo(a)pyrene metabolism with microsomes by addition of uridine 5'-diphosphoglucuronic acid.通过添加尿苷5'-二磷酸葡糖醛酸用微粒体修饰苯并(a)芘代谢。
Cancer Res. 1977 Nov;37(11):4125-9.
3
Glucuronidation of 3-hydroxybenzo(a)pyrene in liver microsomes.肝脏微粒体中3-羟基苯并(a)芘的葡萄糖醛酸化作用。
Med Biol. 1979 Oct;57(5):281-6.
4
Effect of glutathione and uridine 5'-diphosphoglucuronic acid on benzo(a)pyrene mutagenesis in the Salmonella/microsome assay.谷胱甘肽和尿苷5'-二磷酸葡糖醛酸对沙门氏菌/微粒体试验中苯并(a)芘诱变作用的影响。
Dev Toxicol Environ Sci. 1980;8:175-80.
5
Inhibition of glucuronidation of benzo(a)pyrene phenols by long-chain fatty acids.长链脂肪酸对苯并(a)芘酚葡萄糖醛酸化的抑制作用。
Cancer Res. 1991 Sep 1;51(17):4511-5.
6
UDP-glucuronosyl transferase and the conjugation of benzo(a)pyrene metabolites to DNA.尿苷二磷酸葡萄糖醛酸基转移酶与苯并(a)芘代谢产物与DNA的结合
Biochem Biophys Res Commun. 1978 Dec 14;85(3):891-9. doi: 10.1016/0006-291x(78)90627-7.
7
In vitro metabolism of benzo(a)pyrene by human liver microsomes and lymphocytes.苯并(a)芘在人肝微粒体和淋巴细胞中的体外代谢
Cancer Res. 1975 Dec;35(12):3651-5.
8
Effect of UDP-glucuronic acid on the microsome-mediated binding of benzo(a)pyrene metabolites to calf thymus DNA.尿苷二磷酸葡萄糖醛酸对苯并(a)芘代谢物与小牛胸腺 DNA 微粒体介导结合的影响。
Carcinogenesis. 1980 Feb;1(2):115-20. doi: 10.1093/carcin/1.2.115.
9
Metabolism of benzo[a]pyrene-3,6-quinone by isolated hepatocytes.苯并[a]芘-3,6-醌在分离的肝细胞中的代谢
FEBS Lett. 1980 Sep 22;119(1):33-7. doi: 10.1016/0014-5793(80)80992-6.
10
A rapid enzymic procedure for the determination of picomole amounts of UDP-glucuronic acid.一种用于测定皮摩尔量尿苷二磷酸葡萄糖醛酸的快速酶促方法。
Biochem J. 1980 Aug 1;189(2):369-72. doi: 10.1042/bj1890369.

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Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line.多光子光谱分析苯并[a]芘在大鼠肝细胞系中的摄取和代谢。
Toxicol Appl Pharmacol. 2011 May 15;253(1):45-56. doi: 10.1016/j.taap.2011.03.009. Epub 2011 Mar 21.
2
Bioavailability and biotransformation of benzo(a)pyrene in an isolated perfused In situ catfish intestinal preparation.苯并(a)芘在离体灌注原位鲶鱼肠道制剂中的生物利用度和生物转化
Environ Health Perspect. 1998 Mar;106(3):155-66. doi: 10.1289/ehp.98106155.
3
Metabolism of epoxidized phosphatidylcholine by phospholipase A2 and epoxide hydrolase.
环氧磷脂酰胆碱被磷脂酶A2和环氧水解酶的代谢过程。
Lipids. 1981 Nov;16(11):781-9. doi: 10.1007/BF02535029.
4
Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.微粒体和细胞核芳烃单加氧酶、环氧化物水解酶以及细胞质谷胱甘肽S-环氧化物转移酶的特定诱导对致癌物苯并(a)芘在体内与大鼠肝脏DNA共价结合的影响。
J Cancer Res Clin Oncol. 1980;98(2):139-52. doi: 10.1007/BF00405958.
5
Evolution of activation-detoxification enzyme patterns during precarcinogenesis in synergism: 3-methylcholanthrene and dimethylnitrosamine.协同作用下致癌前阶段激活 - 解毒酶模式的演变:3 - 甲基胆蒽与二甲基亚硝胺
J Cancer Res Clin Oncol. 1982;103(3):227-40. doi: 10.1007/BF00409699.
6
Metabolism of xenobiotic compounds by enzymes in cell extracts of the fungus Cunninghamella elegans.线虫状小克银汉霉菌细胞提取物中的酶对外源化合物的代谢作用
Biochem J. 1982 Jul 1;205(1):117-22. doi: 10.1042/bj2050117.
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Role of cytochrome P-450 and related enzymes in the pulmonary metabolism of xenobiotics.细胞色素P-450及相关酶在外源化学物肺代谢中的作用。
Environ Health Perspect. 1984 Apr;55:359-67. doi: 10.1289/ehp.8455359.
8
The protective effect of Thiola against the genotoxic action of benzo(a)pyrene.硫普罗宁对苯并(a)芘遗传毒性作用的保护效果。
Experientia. 1986 May 15;42(5):572-4. doi: 10.1007/BF01946709.
9
Comparison of benzo(a)pyrene metabolism in isolated perfused rat lung and liver.离体灌注大鼠肺和肝脏中苯并(a)芘代谢的比较。
Arch Toxicol. 1987 Jun;60(4):270-7. doi: 10.1007/BF01234665.
10
Dual role of glucuronyl- and sulfotransferases converting xenobiotics into reactive or biologically inactive and easily excretable compounds.葡萄糖醛酸基转移酶和磺基转移酶的双重作用,可将外源性物质转化为具有反应活性或无生物活性且易于排泄的化合物。
Arch Toxicol. 1977 Dec 30;39(1-2):77-85. doi: 10.1007/BF00343277.