Williams C N, Johnston J L, Weldon K L
Can Med Assoc J. 1977 Oct 8;117(7):758-60.
The prevalence of gallstones and gallbladder disease was studied between October 1973 and June 1976 in Canadian Micmac Indian women aged 15 to 50 years in an inland rural community near Shubenacadie, NS. Of 132 women at risk 98 underwent cholecystography, 6 had a history of cholecystectomy (verified from hospital records) and 3 had cholecystectomy because of cholecystitis during the 3 years of the study. Of the 17 abnormal cholecystograms 10 showed radiolucent gallstones, and repeated studies documented gallstones in 6 of the 7 radiographs on which the gallbladder was not visualized. The prevalence of gallstones was found to be 211/1000, and that of gallbladder disease, 240/1000. The peak prevalence was at 30 to 39 years of age. The women with gallbladder disease were significantly more obese and of greater parity than those without gallbladder disease even when age was controlled. The Micmac Indian women of Nova Scotia appear to be at a much higher risk for the development of cholesterol gallstones and gallbladder disease than Caucasian women in Framingham, Massachusetts.
1973年10月至1976年6月期间，对新斯科舍省舒本纳卡迪附近一个内陆农村社区15至50岁的加拿大米克马克印第安妇女的胆结石和胆囊疾病患病率进行了研究。在132名有患病风险的妇女中，98人接受了胆囊造影检查，6人有胆囊切除术史（从医院记录中核实），3人在研究的3年期间因胆囊炎接受了胆囊切除术。在17份异常胆囊造影图中，10份显示有透光性胆结石，对7份未显示胆囊的X光片进行重复检查后，发现其中6份有胆结石。胆结石患病率为211/1000，胆囊疾病患病率为240/1000。患病率高峰出现在30至39岁。即使在控制年龄因素后，患有胆囊疾病的妇女也比未患胆囊疾病的妇女明显更肥胖且生育次数更多。新斯科舍省的米克马克印第安妇女患胆固醇胆结石和胆囊疾病的风险似乎比马萨诸塞州弗雷明汉的白人妇女高得多。
