Maxwell A
Dept of Biochemistry, University of Leicester, UK.
Trends Microbiol. 1997 Mar;5(3):102-9. doi: 10.1016/S0966-842X(96)10085-8.
DNA gyrase is a remarkable enzyme, catalysing the seemingly complex reaction of DNA supercoiling. As gyrase is essential in prokaryotes, it is a good target for antibacterial agents. These agents have diverse chemical structures and interact with gyrase in a variety of ways.
DNA 回旋酶是一种非凡的酶，催化看似复杂的 DNA 超螺旋反应。由于回旋酶在原核生物中至关重要，它是抗菌剂的良好靶点。这些抗菌剂具有多样的化学结构，并以多种方式与回旋酶相互作用。
