Zhang J, Ping W, Chunrong W, Shou C X, Keyou G
Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine, Beijing.
J Nutr. 1997 Mar;127(3):509S-513S. doi: 10.1093/jn/127.3.509S.
The effects on serum lipids of palm oil (PA) used in Chinese diets were compared with those of soybean oil (SO), peanut oil (PE) and lard (LA) in normocholesterolemic subjects and with that of PE in hypercholesterolemic subjects. Normocholesterolemic subjects [120 men, 18-25 y, total cholesterol (TC) 2.8-5.0 mmol/L] were assigned to four groups to consume test diets for six consecutive weeks after a run-in period of 3 wk. About 30% of dietary energy was derived from fat, 75-80% of which came from test oils. In comparison with the entry level, the average serum TC and LDL cholesterol (LDL-C) were 6.7 and 13.1% lower, respectively, in the PA group and 22.8 and 30.7% higher, respectively, (P < 0.05) in the LA group. At the end of the test, serum TC, LDL-C and the ratio of TC/HDL cholesterol (HDL-C) in the PA group were significantly lower than those of the LA group. Hypercholesterolemic subjects (31 men, 20 women, 32-68 y, TC 5.5-7.0 mmol/L) were divided into two groups. For 6 wk, one group (15 men, 10 women) consumed the PA diet; another group (16 men, 9 women) consumed the PE diet. After a 3-wk interval, the two groups interchanged diets for another 6 wk. The test diets again contained about 30% energy from fat, 60-65% of which came from test oils. Compared with entry values, the PA diet caused significant reductions in serum TC, LDL-C and TC/HDL-C during the first 6 wk and also a significant reduction in TC/HDL-C during the second 6 wk. The PE diet had no significant influence on serum lipids in either experimental period.
将中国饮食中使用的棕榈油（PA）对血脂的影响，与正常胆固醇血症受试者中大豆油（SO）、花生油（PE）和猪油（LA）的影响进行比较，并与高胆固醇血症受试者中花生油的影响进行比较。正常胆固醇血症受试者[120名男性，18 - 25岁，总胆固醇（TC）2.8 - 5.0 mmol/L]在经过3周的导入期后被分为四组，连续六周食用试验饮食。约30%的膳食能量来自脂肪，其中75 - 80%来自试验油。与初始水平相比，PA组的平均血清TC和低密度脂蛋白胆固醇（LDL - C）分别降低了6.7%和13.1%，而LA组分别升高了22.8%和30.7%（P < 0.05）。试验结束时，PA组的血清TC、LDL - C以及TC/高密度脂蛋白胆固醇（HDL - C）比值均显著低于LA组。高胆固醇血症受试者（31名男性，20名女性，32 - 68岁，TC 5.5 - 7.0 mmol/L）分为两组。在6周内，一组（15名男性，10名女性）食用PA饮食；另一组（16名男性，9名女性）食用PE饮食。经过3周的间隔后，两组交换饮食再进行6周。试验饮食同样含有约30%来自脂肪的能量，其中60 - 65%来自试验油。与初始值相比，PA饮食在最初6周内使血清TC、LDL - C和TC/HDL - C显著降低，在第二个6周内也使TC/HDL - C显著降低。PE饮食在两个试验期对血脂均无显著影响。
