Liu Zhiyuan, Yuan Jihong, Wen Ping, Guo Xiaofei, Li Kelei, Wang Yinpeng, Liu Ruirui, Guo Yanjun, Li Duo
Institute of Nutrition & Health, Qingdao University, Qingdao 266071, China.
No. 2 Department of Nutrition, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Foods. 2023 May 4;12(9):1894. doi: 10.3390/foods12091894.
Humans have consumed lard for thousands of years, but in recent decades, it has become much less popular because it is regarded as saturated fat. Animal studies showed that lard plus soybean oil (blend oil) was more advantageous for liver health than using either oil alone. This study aims to assess the effects of blend oil on liver function markers in healthy subjects. The 345 healthy subjects were randomized into 3 isoenergetic diet groups with different edible oils (30 g/day) (soybean oil, lard, and blend oil (50% lard and 50% soybean oil)) for 12 weeks. The reductions in both aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were greater in the blend oil group than in the two other groups ( = 0.001 and <0.001 for the interaction between diet group and time, respectively). The reductions in AST and ALT in the blend oil group were more significant compared with those in the soybean oil group ( < 0.001) or lard group ( < 0.001). There were no significant differences in the other liver function markers between the groups. Thus, blend oil was beneficial for liver function markers such as AST and ALT compared with soybean oil and lard alone, which might help prevent non-alcoholic fatty liver disease in the healthy population.
人类食用猪油已有数千年历史，但近几十年来，猪油已变得不那么受欢迎，因为它被视为饱和脂肪。动物研究表明，猪油加豆油（混合油）对肝脏健康比单独使用任何一种油更有益。本研究旨在评估混合油对健康受试者肝功能指标的影响。345名健康受试者被随机分为3个等能量饮食组，分别食用不同的食用油（30克/天）（豆油、猪油和混合油（50%猪油和50%豆油）），为期12周。混合油组天冬氨酸转氨酶（AST）和丙氨酸转氨酶（ALT）的降低幅度均大于其他两组（饮食组与时间的交互作用分别为P = 0.001和P<0.001）。与豆油组（P<0.001）或猪油组（P<0.001）相比，混合油组AST和ALT的降低更为显著。两组之间其他肝功能指标无显著差异。因此，与单独的豆油和猪油相比，混合油对AST和ALT等肝功能指标有益，这可能有助于预防健康人群中的非酒精性脂肪性肝病。
