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扁桃体切除术和腺样体切除术对肥胖且患有睡眠相关呼吸障碍儿童的影响。

Effect of tonsillectomy and adenoidectomy on obese children with sleep-associated breathing disorders.

作者信息

Kudoh F, Sanai A

机构信息

Division of Oto-rhino-laryngology, Chiba Children's Hospital, Japan.

出版信息

Acta Otolaryngol Suppl. 1996;523:216-8.

PMID:9082786
Abstract

In children and adolescents there have been only few reports dealing with Obstructive Sleep Apnea (OSA) associated with morbid obesity. We report here on sleep-associated breathing disorders in morbidly obese children and the effect of adenoidectomy and tonsillectomy on sleep-associated breathing disorders. The subjects were 31 children with morbid obesity. The mean patient age was 7.9 years ranging from 2 to 14 years. The percentage of expected body weight ranged from 130% to 260%. All of them had adeno-tonsillar hypertrophy. We undertook the study during the period of natural sleep. Percentage of sleeping period with irregular breathing was determined by means of respisomnogram and the percentage of sleeping period with SpO(2) > or = 90% with a pulse oximeter. The percentage of sleeping period with irregular breathing ranged from 10% to 85% before the operation. In all cases, the irregular breathing period decreased almost to zero after the adenoidectomy and tonsillectomy. The percentage of sleeping period with SpO(2) > or = 90% ranged from 1.7% to 95%. The percentage was related to reduction of body weight and it increased gradually as a result of a diet given as therapy. Our studies reveal that weight control may result in partial cure of sleep-associated breathing disorders. Operations, such as adenoidectomy and tonsillectomy, were remarkably effective in treating sleep-associated breathing disorders of severely obese children with large adenoids and tonsils, even if the severe obesity remained.

摘要

关于患有病态肥胖症的儿童和青少年阻塞性睡眠呼吸暂停(OSA)的报道很少。我们在此报告病态肥胖儿童睡眠相关呼吸障碍以及腺样体切除术和扁桃体切除术对睡眠相关呼吸障碍的影响。研究对象为31名病态肥胖儿童。患者平均年龄为7.9岁,年龄范围为2至14岁。预期体重百分比范围为130%至260%。他们均有腺样体扁桃体肥大。我们在自然睡眠期间进行研究。通过呼吸睡眠图测定不规则呼吸睡眠时间百分比,并用脉搏血氧仪测定血氧饱和度(SpO₂)≥90%的睡眠时间百分比。手术前不规则呼吸睡眠时间百分比范围为10%至85%。在所有病例中,腺样体切除术和扁桃体切除术后不规则呼吸时间几乎降至零。血氧饱和度≥90%的睡眠时间百分比范围为1.7%至95%。该百分比与体重减轻有关,并且作为治疗给予的饮食使其逐渐增加。我们的研究表明,体重控制可能会部分治愈睡眠相关呼吸障碍。腺样体切除术和扁桃体切除术等手术在治疗患有大腺样体和扁桃体的严重肥胖儿童的睡眠相关呼吸障碍方面非常有效,即使严重肥胖仍然存在。

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