Fratzl P, Schreiber S, Klaushofer K
Materials Physics Institute, University of Vienna, Austria.
Connect Tissue Res. 1996;34(4):247-54. doi: 10.3109/03008209609005268.
Small-angle x-ray scattering (SAXS) can provide information on mean size, predominant orientation and typical shape of mineral crystals in bone. In this paper, recent developments of this technique for application in bone research are reviewed. Then the structure of the collagen/mineral composite in bone, as determined by SAXS, is compared for a number of species. The thickness of the mineral crystals was found to increase with age up to a value around 3 to 4 nanometers in adult animals, depending on the species. The SAXS results also suggest the existence of needle-shaped mineral crystals in mouse or rat bone and more plate-shaped crystals in other tissues like adult human bone or mineralized turkey leg tendon.
小角X射线散射（SAXS）能够提供有关骨骼中矿物晶体的平均尺寸、主要取向和典型形状的信息。本文综述了该技术在骨骼研究中的最新进展。然后，比较了通过SAXS测定的多种物种骨骼中胶原蛋白/矿物质复合物的结构。发现矿物晶体的厚度随年龄增加，在成年动物中达到约3至4纳米的值，这取决于物种。SAXS结果还表明，小鼠或大鼠骨骼中存在针状矿物晶体，而在其他组织如成人骨骼或矿化的火鸡腿肌腱中存在更多的板状晶体。
