Therapeutic approaches for severe Epstein-Barr virus infection.

Epstein-Barr virus, (EBV) is one of the eight known human herpesviruses and is associated with diseases in a spectrum from benign to lethal. Until recently, there has been no definite treatment for severe EBV infection. However, many therapeutic approaches have been attempted, and some of them seem to be beneficial for a certain EBV-associated disease. This review introduces them and provides a more rational basis for the treatment of severe EBV infection.