Kern S B, Andera L
Department of Pathology, Northwest Community Hospital, Arlington Heights, Illinois 60005, USA.
Acta Cytol. 1997 Mar-Apr;41(2):556-60. doi: 10.1159/000332556.
Glycogen-rich (clear cell) carcinoma of the breast is an unusual variant of breast carcinoma that has been described only recently.
We report two cases of glycogen-rich carcinoma with the corresponding fine needle aspiration findings. Cytologically, the presence of a delicate/foamy to clear cytoplasm was the only feature identified to distinguish these tumors from the more common infiltrating duct carcinoma.
Cytologically, the characteristics were not distinctive enough to predict the clear cell nature of the tumor histology. Other breast carcinomas that show optically clear cytoplasm include lipid-rich, secretory, histiocytoid and signet-ring carcinoma. Some cytologic features distinguish them from glycogen-rich carcinoma. Clinical correlation would be required to exclude metastatic clear cell carcinoma from such primaries as the kidney.
乳腺富含糖原（透明细胞）癌是乳腺癌的一种罕见变异类型，直到最近才被描述。
我们报告两例富含糖原癌及其相应的细针穿刺结果。在细胞学上，细腻/泡沫状至透明的细胞质是将这些肿瘤与更常见的浸润性导管癌区分开来的唯一特征。
在细胞学上，这些特征不足以预测肿瘤组织学的透明细胞性质。其他显示光学透明细胞质的乳腺癌包括富含脂质癌、分泌性癌、组织细胞样癌和印戒细胞癌。一些细胞学特征可将它们与富含糖原癌区分开来。需要临床关联以排除来自肾脏等原发部位的转移性透明细胞癌。
