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Development of vicarious trial-and-error behavior in odor discrimination learning in the rat: relation to hippocampal function?

作者信息

Hu D, Griesbach G, Amsel A

机构信息

Department of Psychology, University of Texas, Austin 78712, USA.

出版信息

Behav Brain Res. 1997 Jun;86(1):67-70. doi: 10.1016/s0166-4328(96)02247-4.

DOI:10.1016/s0166-4328(96)02247-4
PMID:9105583
Abstract

Previous work from our laboratory has suggested that hippocampal electrolytic lesions result in a deficit in simultaneous, black-white discrimination learning and reduce the frequency of vicarious trial-and-error (VTE) at a choice-point. VTE is a term Tolman used to describe the rat's conflict-like behavior, moving its head from one stimulus to the other at a choice point, and has been proposed as a major nonspatial feature of hippocampal function in both visual and olfactory discrimination learning. Simultaneous odor discrimination and VTE behavior were examined at three different ages. The results were that 16-day-old pups made fewer VTEs and learned much more slowly than 30- and 60-day-olds, a finding in accord with levels of hippocampal maturity in the rat.

摘要

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