Roman F S, Simonetto I, Soumireu-Mourat B
Laboratoire de Neurobiologie, Université de Provence, Marseille, France.
Behav Neurosci. 1993 Feb;107(1):72-81. doi: 10.1037//0735-7044.107.1.72.
Rats with horizontal diagonal band of Broca (HDBB) lesions were trained in a successive-cue olfactory discrimination using different intertrial intervals (ITIs). They learned the paradigm of the task, but substantial impairment in performance of odor-reward associations was observed when the ITIs were longer than 15 s. They performed as well as control animals with short ITIs when they were trained previously with long ITIs, but forgetting appeared very soon thereafter (24 hr later). The finding is that the HDBB is an essential relay between the hippocampal system and the olfactory cortex: The HDBB allows associative memory storage when a limited-duration short-memory system located elsewhere is overloaded.
对患有布罗卡水平对角带（HDBB）损伤的大鼠进行连续线索嗅觉辨别训练，采用不同的试验间隔时间（ITIs）。它们学会了任务范式，但当ITIs超过15秒时，在气味-奖励关联表现上出现了显著损伤。当它们先前用长ITIs训练后，在短ITIs时表现与对照动物一样好，但此后很快（24小时后）就出现了遗忘。研究结果表明，HDBB是海马体系统与嗅觉皮层之间的重要中继站：当位于其他地方的有限持续时间的短记忆系统过载时，HDBB允许关联记忆存储。
