Kalyoncu A F, Demir A U, Ozcan U, Ozkuyumcu C, Sahin A A, Bariş Y I
Hacettepe University Hospital, Department of Chest Diseases Adult Allergy Unit, Ankara, Turkey.
Ann Allergy Asthma Immunol. 1997 Apr;78(4):408-12. doi: 10.1016/S1081-1206(10)63203-6.
Beekeeping has progressed recently to where bee sting exposure is an important public health problem in Turkey.
To investigate the status of bee and wasp sting allergy in a region of Turkey.
We conducted a questionnaire-based study of 786 subjects (cellulose paper factory personnel and family members older than 16 years of age) in Cay town of Afyon. Skin prick test with common aeroallergens and measurements of total IgE and specific IgE for bee and wasp venom were performed in 212 randomly selected subjects.
Cumulative lifetime sting rate was 94.5% (geometric mean: 6.1 times), and last year bee sting rate was 20.4% (geometric mean: 1.6 times). Subjects who had beehives had higher risk of bee sting (P < .05) in the last year, whereas there was no significant difference among the groups for the cumulative lifetime sting exposure. Severe and mild systemic reactions were noted in 2.2% and 5.3%, respectively. Emergency room visits were reported in 9.3%, and familial Hymenoptera allergy in 10.2%. Fatal potential of bee sting was known by 81%. There was no mortality related with Hymenoptera allergy in records of the last 5 years. In 24 subjects with multiple sting exposures, allergic reactions changed severity in the latter exposures, which became less severe in five and more severe in 19 subjects. Atopy rate detected by prick testing was 20.3%. Specific IgE levels were class 1 in 22, class 2 in 11, and class 3 in 2 subjects for bee; and class 1 in 24 and class 2 in 2 subjects for wasp. Nobody had received immunotherapy for venom allergy. None of the factors including atopy, sex, occupation, smoking and family history of bee sting was significantly related with severity of the systemic reaction (P > .05).
Bee and wasp stings are prevalent in Turkey. Severe systemic reactions complicating the sting are frequent (2.2%). Public awareness of potential fatality and treatment of the allergic reaction is not adequate.
近年来，养蜂业不断发展，在土耳其，蜜蜂蜇伤已成为一个重要的公共卫生问题。
调查土耳其某地区蜜蜂和黄蜂蜇伤过敏的状况。
我们对阿菲永省恰伊镇的786名受试者（纤维素纸厂员工及16岁以上家庭成员）进行了一项基于问卷调查的研究。对212名随机选取的受试者进行了常见气传变应原的皮肤点刺试验，以及蜜蜂和黄蜂毒液总IgE和特异性IgE的检测。
累计终生蜇伤率为94.5%（几何均值：6.1次），去年蜜蜂蜇伤率为20.4%（几何均值：1.6次）。去年有蜂箱的受试者被蜜蜂蜇伤的风险更高（P < 0.05），而各组之间累计终生蜇伤暴露情况无显著差异。分别有2.2%和5.3%的受试者出现严重和轻度全身反应。9.3%的受试者报告曾前往急诊室就诊，10.2%的受试者有家族性膜翅目过敏史。81%的人知道蜜蜂蜇伤有致命风险。在过去5年的记录中，没有与膜翅目过敏相关的死亡病例。在24名多次被蜇伤的受试者中，过敏反应在后续蜇伤中严重程度发生了变化，其中5名受试者的反应变轻，19名受试者的反应加重。点刺试验检测到的特应性率为20.3%。蜜蜂特异性IgE水平为1级的有22名受试者，2级的有11名，3级的有2名；黄蜂特异性IgE水平为1级的有24名受试者，2级的有2名。没有人接受过针对毒液过敏的免疫治疗。包括特应性、性别、职业、吸烟和蜜蜂蜇伤家族史在内的所有因素与全身反应的严重程度均无显著相关性（P > 0.05）。
在土耳其，蜜蜂和黄蜂蜇伤很常见。蜇伤后并发严重全身反应的情况很频繁（2.2%）。公众对潜在致命风险及过敏反应治疗的认知不足。
