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原发性先天性青光眼房角切开术的诊断时间、再次手术情况及长期疗效:一项临床研究

Time of diagnosis, reoperations and long-term results of goniotomy in the treatment of primary congenital glaucoma: a clinical study.

作者信息

Gramer E, Tausch M, Kraemer C

机构信息

University Eye Hospital Würzburg, Germany.

出版信息

Int Ophthalmol. 1996;20(1-3):117-23. doi: 10.1007/BF00212957.

Abstract

PURPOSE

The aim of our study was to get information about the development of visual acuity, visual field and cup-disc ratio of patients with primary congenital glaucoma after IOP-regulating goniotomy by means of a katamnestic inquiry. The preoperative conditions of IOP, corneal diameter and corneal opacity were related to postoperative findings of visual acuity, visual field and cup-disc ratio reported by the treating ophthalmologists.

METHODS

196 patients were contacted, who had a goniotomy in the period from 1965 to 1983 at the University Eye Hospital Würzburg. Out of the 92 returned replies, the address of the treating ophthalmologists could be ascertained from 77 patients. Sixty of the 77 patients fulfilled the inclusion criteria: (1) primary congenital glaucoma and (2) IOP-regulating goniotomy as last surgery.

RESULTS

I. In 76% of 106 eyes childhood glaucoma was diagnosed during the first year of life. II. In 72% of 60 eyes/patients with primary congenital glaucoma one goniotomy was sufficient to reach a normal IOP. In 18% a second and in 10% a third goniotomy was necessary, but without influence on the visual outcome. III. Even in the groups of eyes with a preoperative IOP of more than 40 mmHg, preoperative corneal diameter of more than 13 mm and preoperative severe corneal opacity more than 50% reached a visual acuity of 0.4-1.2 and more than 80% had a normal visual field. Only 9% of the eyes showed a cup-disc ratio of 0.6 or more.

CONCLUSIONS

In primary congenital glaucoma even eyes with high preoperative IOP, large corneal diameters and severe corneal edemas had a good prognosis of visual outcome after goniotomy.

摘要

目的

我们研究的目的是通过随访询问,获取原发性先天性青光眼患者在进行眼压调节性前房角切开术后视力、视野和杯盘比的发展情况。将术前眼压、角膜直径和角膜混浊情况与治疗眼科医生报告的术后视力、视野和杯盘比结果相关联。

方法

联系了196例在1965年至1983年期间于维尔茨堡大学眼科医院接受前房角切开术的患者。在92份回复中,从77例患者处确定了治疗眼科医生的地址。77例患者中的60例符合纳入标准:(1)原发性先天性青光眼;(2)最后一次手术为眼压调节性前房角切开术。

结果

I. 在106只眼中,76%在出生后第一年内被诊断为儿童青光眼。II. 在60例原发性先天性青光眼患者的眼中,72%进行一次前房角切开术就足以使眼压恢复正常。18%的患者需要进行第二次,10%的患者需要进行第三次前房角切开术,但这对视力结果没有影响。III. 即使在术前眼压超过40 mmHg、术前角膜直径超过13 mm以及术前严重角膜混浊超过50%的眼组中,仍有达到0.4 - 1.2的视力,且超过80%的患者视野正常。只有9%的眼杯盘比为0.6或更高。

结论

在原发性先天性青光眼中,即使是术前眼压高、角膜直径大且角膜水肿严重的眼,在前房角切开术后视力预后也良好。

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