Lidman C, Olsson M, Björkman A, Elvin K
Department of Infectious Diseases, University Hospital Huddinge, Sweden.
Scand J Infect Dis. 1997;29(1):63-4. doi: 10.3109/00365549709008666.
Clusters of Pneumocystis carinii pneumonia (PCP) in immunocompromised settings suggest person-to-person transmission. We examined whether personnel in a ward for HIV-infected patients were carriers of P. carinii. None of 29 sputum samples from 19 personnel caring for HIV-infected patients had detectable amounts of P. carinii DNA, as determined by the two PCR methods used. Two of 26 personnel were found, by an immunofluorescence assay, to have serum antibodies for P. carinii. The results do not support the hypothesis that personnel represent major vectors or transient reservoirs for spreading P. carinii infection to immunocompromised hosts.
免疫功能低下情况下卡氏肺孢子虫肺炎（PCP）的聚集提示人际传播。我们检查了一间艾滋病病毒感染患者病房的工作人员是否为卡氏肺孢子虫的携带者。通过所使用的两种聚合酶链反应（PCR）方法测定，19名护理艾滋病病毒感染患者的工作人员的29份痰液样本中均未检测到卡氏肺孢子虫DNA。通过免疫荧光测定法发现，26名工作人员中有两人血清中有卡氏肺孢子虫抗体。结果不支持工作人员是将卡氏肺孢子虫感染传播给免疫功能低下宿主的主要载体或短暂储存宿主这一假说。
