Elliott T B, Yego S, Irvin T T
Department of Surgery, Royal Devon and Exeter Hospital, UK.
Br J Surg. 1997 Apr;84(4):535-9.
The objective of this study was to audit the presentation and outcome for patients admitted with an acute complication of diverticular disease.
This study was a retrospective review of 418 admissions with an acute complication of diverticular disease over a 5-year interval.
Of the 418 admissions, 15 patients were eventually found to have an alternative diagnosis. Some 403 patients were studied further. The overall mortality rate in this group was 5.7 per cent. A total of 113 patients (28.0 per cent) required an operation and in this group the mortality rate was 17.7 per cent. All deaths occurred in patients who had surgery for septic complications or bowel obstruction. Of the patients who had surgery, 90.2 per cent had a resection of the involved colon. One-third of these had a primary anastomosis; the remainder underwent Hartmann's procedure. Some 83 patients had a stoma fashioned and of these 72 went on to have the stoma closed. The median age of those who died after operation was 80 years. An American Society of Anesthesiologists (ASA) score of 3 or more, concurrent medical disease and shock on admission were all associated with a high mortality rate (P < 0.001). Some 30 per cent of patients were readmitted during this study with a further complication of diverticular disease.
The mortality rate after surgery for acute diverticular disease remains excessive and a high-risk group can be identified before operation. A policy of resection and anastomosis appears justified for selected patients. Adopting a practice of interval elective sigmoid colectomy after admission with acute diverticulitis might prevent readmission with further complications.
本研究的目的是审核因憩室病急性并发症入院患者的临床表现及治疗结果。
本研究是一项回顾性研究,对5年间418例因憩室病急性并发症入院的病例进行分析。
在418例入院患者中,最终发现15例有其他诊断。约403例患者被进一步研究。该组患者的总死亡率为5.7%。共有113例患者(28.0%)需要手术治疗,该组患者的死亡率为17.7%。所有死亡病例均发生在因感染性并发症或肠梗阻接受手术的患者中。接受手术的患者中,90.2%切除了受累结肠。其中三分之一进行了一期吻合;其余患者接受了哈特曼手术。约83例患者进行了造口术,其中72例随后进行了造口关闭术。术后死亡患者的中位年龄为80岁。美国麻醉医师协会(ASA)评分为3分或更高、并存内科疾病以及入院时休克均与高死亡率相关(P<0.001)。在本研究期间,约30%的患者因憩室病的进一步并发症再次入院。
急性憩室病手术后的死亡率仍然过高,且术前可识别出高危患者群体。对于部分患者,切除并吻合的策略似乎是合理的。在急性憩室炎入院后采取择期乙状结肠切除术的做法可能会预防因进一步并发症而再次入院。