Zhang J D, Li S
JinZhou Health and Anti-Epidemic Station, JinZhou City, Liao-Ning Province, China.
J Occup Environ Med. 1997 Apr;39(4):315-9. doi: 10.1097/00043764-199704000-00008.
This report is a clarification and further analysis of our previously published mortality study regarding groundwater contamination with hexavalent chromium (Cr+6) in the JinZhou area of China between 1965 and 1978. In our previous report, we stated that a significant excess of overall cancer mortality was observed (P = 0.04) in five Cr(+6)-contaminated villages combined. Further analysis revealed no clear statistical increase in cancer mortality in the three villages adjacent to the source of the contamination (P = 0.25), where 57% of the wells exceeded the European Community safe drinking water standard of 0.05 ppm Cr+6. These results do not indicate an association of cancer mortality with exposure to Cr(+6)-contaminated groundwater, but might reflect the influence of lifestyle or environmental factors not related to Cr+6. Further follow-up of this cohort is recommended.
本报告是对我们之前发表的关于1965年至1978年中国锦州地区地下水六价铬（Cr+6）污染的死亡率研究的澄清和进一步分析。在我们之前的报告中，我们指出，五个受Cr(+6)污染的村庄总体癌症死亡率显著过高（P = 0.04）。进一步分析显示，在靠近污染源的三个村庄中，癌症死亡率没有明显的统计学上升（P = 0.25），其中57%的水井超过了欧盟0.05 ppm Cr+6的安全饮用水标准。这些结果并不表明癌症死亡率与接触受Cr(+6)污染的地下水有关，但可能反映了与Cr+6无关的生活方式或环境因素的影响。建议对该队列进行进一步随访。
