Vories A A, Ramirez S G
Otolaryngology-Head and Neck Surgery Service, Brooke Army Medical Center, San Antonio, Tex 78234-6200, USA.
South Med J. 1997 Apr;90(4):416-8. doi: 10.1097/00007611-199704000-00011.
Warthin's tumor is a relatively uncommon salivary gland neoplasm, traditionally considered a disease of men. Recent reports have brought this assumption into question by identifying a substantial percentage of patients who are women. Furthermore, several reports have attempted to correlate cigarette smoking with development of Warthin's tumor. We retrospectively studied all cases of parotid tumor entered in the Brooke Army Medical Center Tumor Registry from 1973 to 1993. Relative percentages of benign and malignant disease, as well as frequency of individual tumor types, in general mirrored those in earlier reports. A high proportion of Warthin's tumor-23% of all tumors-was identified. More than one third of patients with Warthin's tumor were women. Also, 94% of patients with Warthin's tumor had a history of tobacco use; for all other tumor types combined, only 60% of patients had a history of tobacco use. This statistical difference supports the correlation between cigarette smoking and Warthin's tumor.
沃辛瘤是一种相对罕见的涎腺肿瘤，传统上被认为是男性疾病。最近的报告通过发现相当比例的女性患者对这一假设提出了质疑。此外，有几份报告试图将吸烟与沃辛瘤的发生联系起来。我们回顾性研究了1973年至1993年录入布鲁克陆军医疗中心肿瘤登记处的所有腮腺肿瘤病例。良性和恶性疾病的相对百分比以及个体肿瘤类型的频率总体上与早期报告相似。我们发现了高比例的沃辛瘤——占所有肿瘤的23%。超过三分之一的沃辛瘤患者为女性。此外，94%的沃辛瘤患者有吸烟史；对于所有其他类型的肿瘤患者，只有60%有吸烟史。这一统计学差异支持了吸烟与沃辛瘤之间的关联。
