Strandberg M W
Biophys J. 1977 Nov;20(2):279-83. doi: 10.1016/S0006-3495(77)85549-5.
An integral representation for the membrane admittance in terms of its known current response to a voltage step function is presented. It is demonstrated that the frequency-dependent terms in the contribution to the membrane admittance by the ion-selective conductance of the nerve membrane are proportional to the static conductances. The additional information contained in the real and imaginary parts of the membrane admittance should allow the parameters of the ion conductance to be determined. Eventually, these measurements should also give information about the electric dipole displacement currents of the conductance systems themselves, and about the metabolically supported active ion transport currents that maintain the ion concentration gradients.
本文给出了一种基于膜对电压阶跃函数已知电流响应的膜导纳积分表示。结果表明,神经膜离子选择性电导对膜导纳贡献中的频率相关项与静态电导成正比。膜导纳实部和虚部所包含的额外信息应能确定离子电导的参数。最终,这些测量还应能提供有关电导系统本身的电偶极位移电流以及维持离子浓度梯度的代谢支持的主动离子转运电流的信息。