Nagasaka T, Yasuma T, Awaya S
Department of Ophthalmology, Nagoya National Hospital, Japan.
Nippon Ganka Gakkai Zasshi. 1997 Feb;101(2):180-6.
The receptive field center of double flash resolution (DFR) and of critical flicker fusion frequency (CFF) in a 3 degrees temporal visual field were examined in 11 normal subjects and 19 glaucoma and ocular hypertension patients. In normal subjects, the mean receptive field center of DFR was 2.17 log min of arc2 and that of CFF was 2.55 log min of arc2. In many glaucoma and ocular hypertension cases, the receptive field center of DFR (mean:2.48 log min of arc2) was significantly enlarged and came close to that of CFF (mean:2.53 log min of arc2)(p < 0.01). Although these findings were mostly seen in patients with some visual field changes, they were also encountered in 9 (70%) of the 13 cases with ocular hypertension without any visual field changes and are probably related to poor intraocular pressure control. We considered that the result was due to the dysfunction of the surrounding area of DFR that consists of interaction between sustained and transient functions of the visual pathway. This dysfunction could be closely related to the disorder of alpha-cells that occurs in the early stage of glaucoma.
对11名正常受试者以及19名青光眼和高眼压症患者，检测了其在3度时间视野内双闪光分辨率（DFR）和临界闪烁融合频率（CFF）的感受野中心。在正常受试者中，DFR的平均感受野中心为2.17 log角分²，CFF的平均感受野中心为2.55 log角分²。在许多青光眼和高眼压症病例中，DFR的感受野中心（平均：2.48 log角分²）显著增大，且接近CFF的感受野中心（平均：2.53 log角分²）（p<0.01）。尽管这些发现大多见于有一些视野改变的患者，但在13例无任何视野改变的高眼压症患者中，也有9例（70%）出现了这种情况，这可能与眼压控制不佳有关。我们认为，该结果是由于DFR周围区域功能障碍所致，该区域由视觉通路的持续和瞬态功能之间的相互作用组成。这种功能障碍可能与青光眼早期发生的α细胞紊乱密切相关。
