Cobby T F, Reid M F
University Department of Anaesthesia, Queens Medical Centre, Nottingham.
Br J Anaesth. 1997 Apr;78(4):431-2. doi: 10.1093/bja/78.4.431.
The study was performed to investigate if wound infiltration with 20 ml of 0.5% bupivacaine after abdominal hysterectomy improved analgesia and reduced morphine requirements from a patient-controlled analgesia system during the first 6 h after operation. Forty patients undergoing abdominal hysterectomy were allocated randomly to one of two groups. The study was performed in a double-blind controlled manner. Morphine requirements in the first 6 h after operation were similar in both the control (30.3 mg) and bupivacaine (29.0 mg) groups. Cumulative hourly morphine requirements did not differ significantly between the two groups. Pain scores assessed by visual analogue were similar in both groups.
本研究旨在调查腹部子宫切除术后伤口浸润20毫升0.5%布比卡因是否能改善镇痛效果并减少术后前6小时患者自控镇痛系统的吗啡需求量。40例行腹部子宫切除术的患者被随机分为两组。本研究采用双盲对照方式进行。对照组（30.3毫克）和布比卡因组（29.0毫克）术后前6小时的吗啡需求量相似。两组每小时的累计吗啡需求量无显著差异。两组通过视觉模拟评分法评估的疼痛评分相似。
