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肝脏微血管系统的体内显微镜检查。

In vivo microscopy of the hepatic microvascular system.

作者信息

McCuskey R S, Reilly F D, McCuskey P A, Dimlich R V

出版信息

Bibl Anat. 1979(18):73-6.

PMID:91366
Abstract

In vivo microscopic study of the responses of the various segments of the hepatic microvascular system to adrenergic, cholinergic, and other aminergic substances and their antagonists have revealed the relative distribution of receptor sites in these various vessels. The results also suggest a possible interaction of cholinergic substances with periportal mast cells. The release of serotonin, histamine and possibly other products from these cells results in dramatic alterations in blood flow through the hepatic sinusoids due to the adhesion of leukocytes and platelets to the endothelium.

摘要

对肝微血管系统各节段对肾上腺素能、胆碱能和其他胺能物质及其拮抗剂反应的体内显微镜研究揭示了这些不同血管中受体位点的相对分布。结果还表明胆碱能物质可能与门静脉周围肥大细胞相互作用。这些细胞释放5-羟色胺、组胺以及可能的其他产物,导致白细胞和血小板粘附于内皮,从而使肝血窦内的血流发生显著改变。

相似文献

1
In vivo microscopy of the hepatic microvascular system.肝脏微血管系统的体内显微镜检查。
Bibl Anat. 1979(18):73-6.
2
Hepatic microvascular regulatory mechanisms. VII. Effects of endoportally-infused endotoxin on microcirculation and mast cells in rats.肝微血管调节机制。VII. 经门静脉注入内毒素对大鼠微循环和肥大细胞的影响。
Microcirc Endothelium Lymphatics. 1986;3(1):47-74.
3
Hepatic microvascular regulatory mechanisms. II. Cholinergic mechanisms.肝微血管调节机制。II. 胆碱能机制。
Hepatology. 1982 Mar-Apr;2(2):230-5. doi: 10.1002/hep.1840020207.
4
Hepatic microvascular regulatory mechanisms. III. Aminergic mechanisms as related to mast cells.肝微血管调节机制。III. 与肥大细胞相关的胺能机制。
Int J Microcirc Clin Exp. 1983;2(1):61-73.
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Hepatic microvascular regulatory mechanisms. IX. Effects of compound 48/80 on endotoxin-induced changes in microcirculation and mast cell integrity.肝脏微血管调节机制。IX. 化合物48/80对内毒素诱导的微循环变化和肥大细胞完整性的影响。
Microcirc Endothelium Lymphatics. 1986;3(2):109-28.
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Hepatic microvascular regulatory mechanisms. VI. Effects of lodoxamide tromethamine or phentolamine-HCl on early hemodynamic and glucoregulatory alterations evoked by endotoxin.肝脏微血管调节机制。VI. 氯苯酰甲胺或盐酸酚妥拉明对内毒素诱发的早期血流动力学和糖调节改变的影响。
Microcirc Endothelium Lymphatics. 1985 Jun;2(3):271-92.
7
Hepatic microvascular regulatory mechanisms. V. Effects of lodoxamide tromethamine or phentolamine-HCl on vascular responses elicited by serotonin.肝微血管调节机制。五、氯苯酰甲胺或盐酸酚妥拉明对血清素引发的血管反应的影响。
Microcirc Endothelium Lymphatics. 1984 Dec;1(6):671-89.
8
Hepatic microvascular regulatory mechanisms. XI. Effects of serotonin on intralobular perfusion and volumetric flowrates at the inlet of periportal and outlet of centrivenous sinusoids.肝微血管调节机制。十一、血清素对门静脉周围窦状隙入口处小叶内灌注及中央静脉窦状隙出口处容积流量的影响。
Microcirc Endothelium Lymphatics. 1991;7(1-3):57-75.
9
Hepatic microvascular regulatory mechanisms. VIII. Glucogenic responses and morphologic changes following serotonin-induced low flow.肝脏微血管调节机制。VIII. 血清素诱导低血流后的糖异生反应及形态学变化。
Microcirc Endothelium Lymphatics. 1986;3(1):21-46.
10
Modulation of the spontaneous histamine release by adrenergic and cholinergic drugs.肾上腺素能和胆碱能药物对组胺自发释放的调节作用。
Agents Actions. 1978 Jun;8(4):347-58. doi: 10.1007/BF01968614.

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In vivo microscopic observations of the responses of Kupffer cells and the hepatic microcirculation to Mycobacterium bovis BCG alone and in combination with endotoxin.
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Infect Immun. 1983 Oct;42(1):362-7. doi: 10.1128/iai.42.1.362-367.1983.
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