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社区老年人群中阿尔茨海默病的诊断:脑电图与磁共振成像的比较

Diagnosing Alzheimer's disease in community-dwelling elderly: a comparison of EEG and MRI.

作者信息

Strijers R L, Scheltens P, Jonkman E J, de Rijke W, Hooijer C, Jonker C

机构信息

Department of Clinical Neurophysiology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands.

出版信息

Dement Geriatr Cogn Disord. 1997 May-Jun;8(3):198-202. doi: 10.1159/000106631.

Abstract

In a study on the course of cognitive impairment in people over 65 years of age, 58 randomly selected community dwelling elderly underwent EEG and MRI studies. The EEG was visually and quantitatively (qEEG) assessed. Nine out of 58 subjects appeared to have Alzheimer dementia (AD) according to CAMDEX criteria. In this group medial temporal lobe atrophy on MRI, as an objective criterium for AD, showed a total accuracy of 72%, visually assessed EEG 81% and qEEG 81-84%. There was an incomplete overlap in subjects regarding MRI and EEG abnormalities, implying that both methods may be complementary.

摘要

在一项针对65岁以上人群认知障碍病程的研究中,58名随机选取的社区老年居民接受了脑电图(EEG)和磁共振成像(MRI)检查。对脑电图进行了视觉和定量(定量脑电图,qEEG)评估。根据剑桥老年精神状态检查表(CAMDEX)标准,58名受试者中有9名似乎患有阿尔茨海默病性痴呆(AD)。在该组中,MRI上的内侧颞叶萎缩作为AD的客观标准,总准确率为72%,视觉评估脑电图为81%,定量脑电图为81 - 84%。在MRI和脑电图异常方面,受试者之间存在不完全重叠,这意味着两种方法可能具有互补性。

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