Watts J L, Salmon S A, Sanchez M S, Yancey R J
Animal Health Discovery Research, Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001, USA.
Antimicrob Agents Chemother. 1997 May;41(5):1190-2. doi: 10.1128/AAC.41.5.1190.
The in vitro activity of premafloxacin against 673 veterinary pathogens was evaluated. Premafloxacin was equivalent to ciprofloxacin, enrofloxacin, and danofloxacin in activity against the gram-negative bacilli but was much more active (MIC for 90% of the strains tested [MIC90], 0.015 to 0.25 microg/ml) than the comparison antimicrobial agents (MIC90, 0.13 to 16.0 microg/ml) against the staphylococci, streptococci, and anaerobes tested.
对普马沙星针对673种兽医病原体的体外活性进行了评估。普马沙星在抗革兰氏阴性杆菌活性方面与环丙沙星、恩诺沙星和达氟沙星相当,但在针对所测试的葡萄球菌、链球菌和厌氧菌方面,其活性(90%测试菌株的最低抑菌浓度[MIC90]为0.015至0.25微克/毫升)比对照抗菌剂(MIC90为0.13至16.0微克/毫升)高得多。