Riley M G, Russell E G, Callinan R B
J Am Vet Med Assoc. 1977 Oct 1;171(7):649-51.
Septicemic disease occurred in 49 of 126 pigs several days after being transported 80 km. All affected pigs died. The main changes in acutely affected pigs were skin discoloration, pulmonary edema, arthritis, meningitis, and renal glomerular thrombosis. In peracute cases, gross findings were minimal. Haemophilus parasuis was isolated from multiple organ sites in most affected pigs. Haemophilus parasuis was isolated from nasal swab specimens from 17 of 20 clinically normal pigs on the farm of origin. Fatal acute septicemia was reproduced in 2 pigs by intravenous or intratracheal exposure to an isolant of H parasuis obtained from 1 of of the 49 fatally affected pigs. Aerosol exposure of 5 pigs resulted in mild pneumonia in 4 pigs and severe pneumonia, pleurisy, pericarditis, and terminal septicemia in 1 pig.
126头猪在被运送80公里几天后，49头发病，均死亡。急性发病猪的主要变化为皮肤变色、肺水肿、关节炎、脑膜炎和肾小球血栓形成。超急性病例肉眼可见病变极少。多数发病猪的多个器官部位分离出副猪嗜血杆菌。在原猪场的20头临床正常猪中，有17头的鼻拭子标本分离出副猪嗜血杆菌。从49头病死猪中的1头所分离的副猪嗜血杆菌菌株，经静脉或气管内接种，使2头猪发生了致死性急性败血症。5头猪经气溶胶暴露，4头发病为轻度肺炎，1头发病为严重肺炎、胸膜炎、心包炎并最终发生败血症。
