Banerjee U, Gupta K, Venugopal P
Department of Microbiology, AIIMS, New Delhi, India.
J Med Vet Mycol. 1997 Mar-Apr;35(2):139-41.
A case of prosthetic valve endocarditis caused by Cryptococcus neoformans var. neoformans is described. The infection followed closed mitral valvotomy and insertion of a valvular prosthesis. Infection was manifested 2 weeks after the operation. The diagnosis was based on direct demonstration of the yeast with characteristic morphology in clinical material, isolation from an arterial thrombus and detection of cryptococcal antigen in the serum. The patient's infection could not be resolved despite institution of antifungal therapy.
本文描述了1例由新型隐球菌新型变种引起的人工瓣膜心内膜炎病例。感染发生在闭式二尖瓣切开术及人工瓣膜植入术后。感染在术后2周出现。诊断依据是在临床材料中直接发现具有特征形态的酵母，从动脉血栓中分离出病原体以及血清中隐球菌抗原的检测。尽管进行了抗真菌治疗，患者的感染仍未得到解决。
