Mettlin C J, Menck H R, Winchester D P, Murphy G P
Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
Cancer. 1997 May 15;79(10):2052-61. doi: 10.1002/(sici)1097-0142(19970515)79:10<2052::aid-cncr29>3.0.co;2-s.
The National Cancer Data Base (NCDB) is an information resource and program evaluation tool of the American College of Surgeons Commission on Cancer and the American Cancer Society that uses a hospital-based cancer reporting system. The Surveillance, Epidemiology, and End Results (SEER) program is a population-based registry program of the National Cancer Institute. The purpose of this investigation was to compare the aggregate NCDB data for selected cancer types from a given year with comparable SEER data.
SEER data from 1992 on 18,322 breast, 13,427 colorectal, 15,276 lung, and 21,501 prostate cancers were compared with NCDB data on 96,323 breast, 69,456 colorectal, 108,702 lung, and 107,690 prostate cancers.
Similar levels of data completeness were observed. The NCDB data tended to contain less complete information about the Spanish or Hispanic ethnicity of patients. Tumor grade data tended to be incomplete in both series. Stage information about lung and prostate cancer was more often missing in SEER data. Patient age, race, and gender in NCDB data differed little from corresponding SEER data, except that SEER data reported a greater proportion of patients in the "other" race category that included Asian-Americans and American Indians. Tumor laterality, anatomic site, tumor grade, and types of surgical treatment were similar in the NCDB and SEER data. Radical mastectomy was performed in 49.4% of SEER breast cancer cases compared with 49.2% of NCDB cases. Cancer-directed surgery was observed less often among SEER prostate cancer cases than among NCDB cases. The NCDB data also indicated greater use of radiation therapy than the SEER data for the four types of cancer reviewed.
The 1992 NCDB data, in aggregate, described patient and disease treatment characteristics and patterns that differed only marginally from those described in the SEER data from the same year.
国家癌症数据库（NCDB）是美国外科医师学会癌症委员会和美国癌症协会的一个信息资源及项目评估工具，它采用基于医院的癌症报告系统。监测、流行病学和最终结果（SEER）项目是美国国立癌症研究所的一个基于人群的登记项目。本研究的目的是将特定年份选定癌症类型的NCDB汇总数据与可比的SEER数据进行比较。
将1992年SEER关于18322例乳腺癌、13427例结直肠癌、15276例肺癌和21501例前列腺癌的数据与NCDB关于96323例乳腺癌、69456例结直肠癌、108702例肺癌和107690例前列腺癌的数据进行比较。
观察到数据完整性水平相似。NCDB数据往往包含关于患者西班牙裔或拉丁裔种族的信息较少。两个系列中的肿瘤分级数据往往不完整。SEER数据中关于肺癌和前列腺癌的分期信息更常缺失。NCDB数据中的患者年龄、种族和性别与相应的SEER数据差异不大，只是SEER数据报告的“其他”种族类别（包括亚裔美国人和美洲印第安人）患者比例更高。NCDB和SEER数据中的肿瘤侧别、解剖部位、肿瘤分级和手术治疗类型相似。SEER乳腺癌病例中有49.4%进行了根治性乳房切除术，而NCDB病例中这一比例为49.2%。在SEER前列腺癌病例中观察到的针对癌症的手术比NCDB病例中少。NCDB数据还表明，在所审查的四种癌症类型中，放射治疗的使用比SEER数据更多。
总体而言，1992年NCDB数据所描述的患者和疾病治疗特征及模式与同年SEER数据所描述的特征及模式仅存在微小差异。
