人体尿液中苯甲酰爱康宁的检测
Detection of benzoylecgonine in human urine.
作者信息
Mueller M A, Adams S M, Lewand D L, Wang R I
出版信息
J Chromatogr. 1977 Nov 21;144(1):101-7. doi: 10.1016/0021-9673(77)80011-3.
A thin-layer chromatography (TLC) method is described that can be used to detect benzoylecgonine (BE), a metabolite of cocaine, in human urine. It is a two-part procedure that can be integrated into a rapid screening program for drug abuse. The first part of the method utilizes two TLC solvent systems to identify a variety of drugs, including BE. The second part is specific for the cocaine metabolite and can be used as a confirmation method. The procedure is sensitive to 3-4 microgram/ml of BE in urine.
本文描述了一种薄层色谱（TLC）方法，该方法可用于检测人尿液中可卡因的代谢物苯甲酰芽子碱（BE）。这是一个可整合到药物滥用快速筛查程序中的两部分流程。该方法的第一部分利用两种TLC溶剂系统来鉴定包括BE在内的多种药物。第二部分对可卡因代谢物具有特异性，可作为确认方法。该程序对尿液中3 - 4微克/毫升的BE敏感。
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