Sant'Anna C A, Solé D, Naspitz C K
Department of Pediatrics, Universidade Federal de São Paulo-Escola, Paulista de Medicina, Brazil.
Pediatr Allergy Immunol. 1996 Nov;7(4):187-92. doi: 10.1111/j.1399-3038.1996.tb00131.x.
We evaluated the prevalence of short stature (SS) among children with respiratory allergic disease followed up in a specialised centre. These patients (N = 617; 8 months to 16 years) with respiratory allergy (asthma and/or rhinitis) were evaluated for SS (stature shorter than the 3rd percentile, NCHS pattern). The possible links between SS and gender; current age; type, severity, and duration of the allergic disease, treatment with corticosteroid and birth weight were also studied. To assess the influence of the socioeconomic level on SS frequency among atopics, 120 of these patients were compared to their non-atopics siblings. The overall prevalence of SS was 7.9%. Relationship between SS and gender type and severity of the allergic disease and treatment with corticosteroids were not observed. A significant higher frequency of SS occurred among patients with longer period of disease and birth weight less than 2,500 gr. Analysis of the pairs of brothers showed significant higher frequency of SS between allergics (12.5% x 4.2%) showing influence of allergic disease per se. Longitudinal studies for long periods of time are required to properly establish the relation between atopic disease and SS.
我们评估了在一家专业中心接受随访的患有呼吸道过敏性疾病儿童的矮小症(SS)患病率。对这些患有呼吸道过敏(哮喘和/或鼻炎)的患者(N = 617;8个月至16岁)进行了矮小症评估(身高低于第3百分位数,采用美国国家卫生统计中心标准)。还研究了矮小症与性别、当前年龄、过敏性疾病的类型、严重程度和病程、皮质类固醇治疗以及出生体重之间的可能联系。为了评估社会经济水平对特应性患者矮小症发生率的影响,将其中120名患者与其非特应性兄弟姐妹进行了比较。矮小症的总体患病率为7.9%。未观察到矮小症与性别、过敏性疾病的类型和严重程度以及皮质类固醇治疗之间的关系。病程较长且出生体重低于2500克的患者中,矮小症的发生率显著更高。对兄弟对的分析显示,过敏患者之间矮小症的发生率显著更高(12.5%对4.2%),表明过敏性疾病本身的影响。需要进行长时间的纵向研究,以正确确立特应性疾病与矮小症之间的关系。