Crifasi J, Long C
Saint Louis University Medical School, Department of Pathology, Berkeley, Missouri 63134, USA.
Forensic Sci Int. 1997 Apr 18;86(1-2):103-8. doi: 10.1016/s0379-0738(97)02126-9.
A fatal overdose involving tranylcypromine (Parnate) where blood, urine and tissues were quantitated using a pentafluoroproprionic anhydride (PFPA) derivative and gas-chromatography/mass spectroscopy (GCMS). The samples were re-quantified over several weeks demonstrating a significant loss of drug in tissues but not blood or urine specimens. The urine was positive for methamphetamine which has been a suspected metabolite.
一起涉及反苯环丙胺（帕那特）的致命过量用药案例，其中使用五氟丙酸酐（PFPA）衍生物和气相色谱/质谱联用仪（GCMS）对血液、尿液和组织进行了定量分析。在数周内对样本进行了重新定量，结果显示组织中的药物有显著损失，但血液和尿液样本中没有。尿液中检测出甲基苯丙胺呈阳性，甲基苯丙胺一直被怀疑是其代谢物。
