Smith D R, Kobrine A I, Rizzoli H V
J Neurol Sci. 1977 Sep;33(3):347-52. doi: 10.1016/0022-510x(77)90132-0.
Blood flow was measured in the sciatic nerve of cats utilizing the method of hydrogen polarography. The mean baseline blood flow for all animals was found to be 47.1 ml/100 g/min +/- 14.9 SD. The flow changes produced by lowering the blood pressure by exsanguination and elevation by the use of angiotensin were then evaluated. The highest (normal) levels of blood flow were observed between the mean blood pressures of 80-110 mm Hg. At mean systemic arterial pressures of less than 85, there was a marked decrease in peripheral nerve blood flow with no detectable flow being measured below mean systemic pressures of 50 mm Hg. Above 105 mm Hg mean arterial pressure, there was a very gradual and progressive decline in blood flow to the levels measured at 200 mm Hg. These findings indicate a complete absence of vascular autoregulation in the peripheral nerve trunks.
采用氢极谱法测量猫坐骨神经中的血流量。发现所有动物的平均基线血流量为47.1毫升/100克/分钟±14.9标准差。然后评估通过放血降低血压和使用血管紧张素升高血压所产生的血流变化。在平均血压80 - 110毫米汞柱之间观察到最高（正常）血流水平。在平均全身动脉压低于85时，外周神经血流量显著下降，在平均全身压低于50毫米汞柱时未检测到血流。平均动脉压高于105毫米汞柱时，血流非常缓慢且逐渐下降至200毫米汞柱时测得的水平。这些发现表明外周神经干完全不存在血管自动调节。
