Acrylamide autonomic neuropathy in the cat. Part 1. Neurophysiological and histological studies.

Neurophysiological and histological studies have been performed on the sympathetic nervous system of cats poisoned with acrylamide. The neurophysiological studies indicate that the large and small diameter myelinated fibres are damaged in the sympathetic nervous system in association with damage to the fibres of the peripheral nervous system. Quantative histological studies confirmed and extended the neurophysiological findings; there was a loss of myelinated fibres of all diameters from the sympathetic, parasympathetic and peripheral nervous system.