粒细胞埃立克体属从人和马源在诱导分化为功能性粒细胞的HL-60细胞中的传播。
Propagation of granulocytic Ehrlichia spp. from human and equine sources in HL-60 cells induced to differentiate into functional granulocytes.
作者信息
Heimer R, Van Andel A, Wormser G P, Wilson M L
机构信息
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520-8034, USA.
出版信息
J Clin Microbiol. 1997 Apr;35(4):923-7. doi: 10.1128/jcm.35.4.923-927.1997.
Abstract
Ehrlichia spp. from human and equine sources in the northeastern Unites States were detected by PCR, isolated, and propagated in the HL-60 promyelocytic leukemia cell line. Growth of Ehrlichia from both equine and human sources was enhanced by addition of retinoic acid, which causes granulocytic differentiation of the HL-60 cells. DNA sequencing of a portion of the 16S rDNA gene supported the hypothesis that the same pathogen was responsible for both equine and human granulocytic ehrlichiosis.
摘要
通过聚合酶链反应（PCR）检测了来自美国东北部人类和马源的埃立克体属细菌，进行分离，并在HL-60早幼粒细胞白血病细胞系中传代培养。添加视黄酸可促进来自马源和人源的埃立克体生长，视黄酸可使HL-60细胞发生粒细胞分化。16S核糖体DNA（rDNA）基因部分序列的DNA测序支持了以下假说：同一病原体导致了马和人的粒细胞埃立克体病。
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本文引用的文献
1
Emergence of the ehrlichioses as human health problems.埃立克体病作为人类健康问题的出现。
Emerg Infect Dis. 1996 Jan-Mar;2(1):18-29. doi: 10.3201/eid0201.960102.
2
Equine granulocytic ehrlichiosis in Connecticut caused by an agent resembling the human granulocytotropic ehrlichia.康涅狄格州的马粒细胞埃立克体病由一种类似于人粒细胞埃立克体的病原体引起。
J Clin Microbiol. 1996 Feb;34(2):434-5. doi: 10.1128/jcm.34.2.434-435.1996.
3
Direct cultivation of the causative agent of human granulocytic ehrlichiosis.人粒细胞埃立克体病病原体的直接培养
N Engl J Med. 1996 Jan 25;334(4):209-15. doi: 10.1056/NEJM199601253340401.
4
Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease.鉴定一种嗜粒细胞埃立克体菌种为人类疾病的病原体。
J Clin Microbiol. 1994 Mar;32(3):589-95. doi: 10.1128/jcm.32.3.589-595.1994.
5
Ixodes dammini as a potential vector of human granulocytic ehrlichiosis.达氏硬蜱作为人类粒细胞埃立克体病的潜在传播媒介。
J Infect Dis. 1995 Oct;172(4):1007-12. doi: 10.1093/infdis/172.4.1007.
6
Identification of the causative agent of granulocytic ehrlichiosis in Swedish dogs and horses by direct solid phase sequencing of PCR products from the 16S rRNA gene.通过对来自16S rRNA基因的PCR产物进行直接固相测序，鉴定瑞典犬类和马匹中粒细胞埃立克体病的病原体。
Res Vet Sci. 1995 Mar;58(2):109-12. doi: 10.1016/0034-5288(95)90061-6.
7
Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.维甲酸诱导人早幼粒细胞白血病细胞系（HL-60）分化
Proc Natl Acad Sci U S A. 1980 May;77(5):2936-40. doi: 10.1073/pnas.77.5.2936.
8
Control of HL-60 monocytic differentiation. Different pathways and uncoupled expression of differentiation markers.
Exp Cell Res. 1987 Jan;168(1):247-54. doi: 10.1016/0014-4827(87)90432-0.
9
The tribe Ehrlichieae and ehrlichial diseases.埃立克体族与埃立克体病
Clin Microbiol Rev. 1991 Jul;4(3):286-308. doi: 10.1128/CMR.4.3.286.
10
Ehrlichia chaffeensis, a new species associated with human ehrlichiosis.查菲埃立克体，一种与人类埃立克体病相关的新物种。
J Clin Microbiol. 1991 Dec;29(12):2838-42. doi: 10.1128/jcm.29.12.2838-2842.1991.
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