Desai U R, Alhalel A A, Schiffman R M, Campen T J, Sundar G, Muhich A
Department of Ophthalmology, Henry Ford Health Sciences Center, Detroit, MI, USA.
Ophthalmology. 1997 May;104(5):781-6. doi: 10.1016/s0161-6420(97)30233-4.
The purpose of the study is to determine the incidence, timing, and severity of variability in the intraocular pressures (IOPs) from baseline after simple pars plana vitrectomy.
A prospective study was performed in 25 consecutive patients undergoing simple pars plana vitrectomy. Intraocular pressures were measured before surgery, immediately after surgery, and then at 2, 4, 6, 12, and 24 hours after surgery.
The mean IOP was elevated significantly 2 hours after surgery when compared with the mean immediate postoperative IOP (30.3 mmHg +/- 11.0 mmHg vs. 17.4 mmHg +/- 7.0 mmHg, P < 0.001). A steady decline was seen at all succeeding timepoints. The 24-hour mean (17.3 mmHg +/- 4.3 mmHg, P = 0.923) was similar to baseline. Ninety-two percent of eyes had a 2-hour postoperative IOP that was higher than the IOP at the completion of surgery. Forty percent of patients required medical management for IOP greater than or equal to 30 mmHg.
Significant IOP elevation can occur after simple pars plana vitrectomy. The optimal time for detecting the pressure rise during the first 24 hours is 2 hours after surgery.
本研究的目的是确定单纯玻璃体切割术后眼内压(IOP)相对于基线的变化发生率、时间及严重程度。
对连续25例行单纯玻璃体切割术的患者进行前瞻性研究。在手术前、手术后即刻以及术后2、4、6、12和24小时测量眼内压。
与术后即刻平均眼内压相比,术后2小时平均眼内压显著升高(30.3 mmHg ± 11.0 mmHg对17.4 mmHg ± 7.0 mmHg,P < 0.001)。在所有后续时间点均可见眼内压稳步下降。24小时平均眼内压(17.3 mmHg ± 4.3 mmHg,P = 0.923)与基线相似。92%的患眼术后2小时的眼内压高于手术结束时的眼内压。40%的患者因眼内压大于或等于30 mmHg需要药物治疗。
单纯玻璃体切割术后可出现显著的眼内压升高。术后24小时内检测眼压升高的最佳时间是术后2小时。