Leonova M V, Belousov Iu B, Semenchuk G A, Malysheva E A, Upnitskiĭ A A, Istratov S Iu
Ter Arkh. 1997;69(1):35-8.
The authors have found that more accurate prognosis of left ventricular myocardial hypertrophy (LVMH) may be made basing on fluctuations and variability of arterial pressure throughout the day: significant fluctuations of arterial pressure at night and pronounced variability of systolic arterial pressure in the day time and at night are indicative of essential hypertension instability and may contribute to LVMH progression. Of still greater prognostic significance is assessment of 24-h arterial pressure rhythm by the degree of a night fall (DNF) in diastolic arterial pressure (DAP). A disturbed 24-h rhythm of arterial pressure (a fall in DNF of DAP) is a predictor of LVMH development.
作者发现，基于全天动脉血压的波动和变异性，可能对左心室心肌肥厚（LVMH）做出更准确的预后判断：夜间动脉血压的显著波动以及白天和夜间收缩期动脉血压的明显变异性表明原发性高血压不稳定，可能促使LVMH进展。通过舒张压（DAP）的夜间下降幅度（DNF）来评估24小时动脉血压节律，其预后意义更大。动脉血压的24小时节律紊乱（DAP的DNF下降）是LVMH发生的一个预测指标。
