Sawanpanyalert P, Uthaivoravit W, Yanai H, Limpakarnjanarat K, Mastro T D, Nelson K E
Department of Medical Services, Ministry of Public Health, Muang Nonthaburi, Thailand.
Int J Epidemiol. 1997 Apr;26(2):408-13. doi: 10.1093/ije/26.2.408.
The epidemic of Human Immunodeficiency Virus (HIV) infection led blood banks to initiate donation deferral criteria based on self-reported risk factors. However little information is available on the differences in reporting risk factors before and after HIV status is known.
Between April and July 1994, blood donors in a provincial hospital in northern. Thailand were interviewed at the time of donation, about their demographic characteristics and risk factors. All donors had agreed to learn their test results and were called back for post-test counselling and reinterview.
HIV-positive blood donors were more likely to change from 'denying' to 'acknowledging' risk factors while HIV-negatives were more likely to change from 'acknowledging' to 'denying'. The differences between risk factors obtained before and after test results were known resulted in stronger, weaker or even opposite risk measures.
The study results raise questions about the impact of the differences in reporting HIV-related risk factors by the donors on how effective donation deferral criteria can be developed.
人类免疫缺陷病毒(HIV)感染的流行促使血库根据自我报告的风险因素制定献血延期标准。然而,关于在知晓HIV感染状况前后报告风险因素的差异,目前所知甚少。
1994年4月至7月间,对泰国北部一家省级医院的献血者在献血时进行了访谈,询问他们的人口统计学特征和风险因素。所有献血者均同意了解其检测结果,并被召回进行检测后咨询和重新访谈。
HIV阳性献血者更有可能从“否认”风险因素转变为“承认”,而HIV阴性献血者更有可能从“承认”转变为“否认”。在知晓检测结果前后所获得的风险因素之间的差异,导致了更强、更弱甚至相反的风险衡量指标。
研究结果引发了关于献血者报告与HIV相关风险因素的差异对制定有效的献血延期标准的影响的问题。