Fratino P, Jucci A, Criffò A, Gatto F, Perlasca S
Minerva Med. 1977 Sep 22;68(44):3061-72.
Radiochemical evaluation of serum insulin-binding activity in diabetics shows that there are no correlations between this behaviour and diabetic retinopathy. High values are mainly encountered in insulin-dependent diabetics; its nil or poor inhibition, owing to the effect of preincubation of the serum with high concentrations of unlabelled insulinic antigen, suggests that the phenomenon is connected above all to the presence of aspecific serous factors that "bind" the labelled hormone.
糖尿病患者血清胰岛素结合活性的放射化学评估表明，这种行为与糖尿病视网膜病变之间没有相关性。高值主要出现在胰岛素依赖型糖尿病患者中；由于血清与高浓度未标记胰岛素抗原预孵育的影响，其抑制作用为零或较弱，这表明该现象首先与“结合”标记激素的非特异性血清因子的存在有关。
