Lohinai Z, Székely A D, Benedek P, Csillag A
Experimental Research Department and Second Institute of Physiology, Semmelweis University of Medicine, Budapest, Hungary.
Neurosci Lett. 1997 May 16;227(2):91-4. doi: 10.1016/s0304-3940(97)00319-4.
In a previous study we found that nitric oxide (NO) plays an essential role in the hemodynamic regulation of the feline dental pulp. However, no evidence for the presence of nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) containing nerve fibers was found in the rat and cat dental pulps. In the present study, we are first to report the presence of a small number of NADPH-d positive and/or NO synthase immunoreactive perivascular and solitary varicose axons in the dental pulp and abundant number of similar axons in the gingiva of cats and dogs. These fibres may travel within the inferior alveolar nerve and might participate in sensory (i.e. pain) as well as in autonomic (i.e. regulation of blood flow) innervation of the dental pulp and gingiva.
在先前的一项研究中，我们发现一氧化氮（NO）在猫牙髓的血流动力学调节中起重要作用。然而，在大鼠和猫的牙髓中未发现含有烟酰胺腺嘌呤二核苷酸磷酸黄递酶（NADPH-d）的神经纤维存在的证据。在本研究中，我们首次报告在猫和狗的牙髓中存在少量NADPH-d阳性和/或一氧化氮合酶免疫反应性血管周围和孤立曲张轴突，并且在牙龈中存在大量类似的轴突。这些纤维可能在下牙槽神经内走行，并可能参与牙髓和牙龈的感觉（即疼痛）以及自主（即血流调节）神经支配。
