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[经历温度构象转变的配体对DNA双螺旋稳定性的影响]

[The effect of ligands undergoing temperature conformational transitions on the stability of DNA double helix].

作者信息

Lando D Iu

出版信息

Biofizika. 1997 Jan-Feb;42(1):92-8.

PMID:9181807
Abstract

The influence of ligands, which undergo conformational transition, on DNA molecular melting is considered theoretically. Equations for computation of melting curves of DNA included in such complexes are obtained, which are used for studies of DNA double helix stability and of the binding to helical and coil regions influence on ligand conformational transitions. Calculated melting curves and experimental data for DNA-RNAase complex are compared.

摘要

从理论上考虑了经历构象转变的配体对DNA分子解链的影响。得到了此类复合物中所含DNA解链曲线的计算方程，这些方程用于研究DNA双螺旋稳定性以及螺旋区和卷曲区的结合对配体构象转变的影响。比较了DNA - RNA酶复合物的计算解链曲线和实验数据。

相似文献

1
[The effect of ligands undergoing temperature conformational transitions on the stability of DNA double helix].[经历温度构象转变的配体对DNA双螺旋稳定性的影响]
Biofizika. 1997 Jan-Feb;42(1):92-8.
2
[Effect of selectively reacting ligands on the helix-coil transition of DNA. III. Calculation of the melting curves of DNA-ligand complexes].[选择性反应配体对DNA螺旋-线圈转变的影响。III. DNA-配体复合物解链曲线的计算]
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3
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[Effect of additional links weakening or stabilizing the double helix at the melting point of DNA].
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A theoretical consideration of the influence of selective binding of small ligands on DNA helix-coil transition.小配体选择性结合对DNA螺旋-线圈转变影响的理论思考。
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