Kirk M, Pace S
Indiana Poison Control Center, Emergency Medicine and Trauma Center, Methodist Hospital, Indianapolis, USA.
Emerg Med Clin North Am. 1997 May;15(2):427-49. doi: 10.1016/s0733-8627(05)70309-6.
Pearls and pitfalls learned from our practical experiences caring for poisoned patients are presented. Clinical pearls include the following: using diagnostic tests to detect end-organ toxicity, applying physiologic principles to the management of hemodynamically unstable poisoned patients, and dealing with psychologic injuries from hazardous materials incidents. Recognizing serious complications from poisoning and adverse drug effects, including the serotonin syndrome, are offered as pitfalls. Pharmaceutical companies are rapidly developing and marketing new therapies. Therefore, updates on the evolving role of NAC as an antidote for acetaminophen poisoning, new psychotropic medications, and new antidotes were included in this article. These pearls, pitfalls, and updates are intended to provide practical information that is readily applicable to the clinical practice of emergency medicine.
本文介绍了我们在照顾中毒患者的实际经验中所学到的要点和陷阱。临床要点包括：使用诊断测试来检测终末器官毒性，运用生理学原理来管理血流动力学不稳定的中毒患者，以及处理有害物质事件造成的心理伤害。认识到中毒和药物不良反应的严重并发症，包括血清素综合征，被列为陷阱。制药公司正在迅速开发和推广新疗法。因此，本文还纳入了关于N-乙酰半胱氨酸作为对乙酰氨基酚中毒解毒剂的不断演变的作用、新型精神药物和新解毒剂的最新信息。这些要点、陷阱和更新旨在提供易于应用于急诊医学临床实践的实用信息。
