Vaughan-Scott T, Taylor J H
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
J S Afr Vet Assoc. 1997 Mar;68(1):21-5. doi: 10.4102/jsava.v68i1.861.
Osteoarthritis or degenerative joint disease is a condition characterised by degeneration of articular cartilage often associated with the formation of new bone at joint surfaces on margins. Commonly encountered in dogs, osteoarthritis may have a gradual onset, but may also occur acutely. Osteoarthritis can be a primary disease of joint cartilage, but is more after secondary to abnormal stresses on joints. This article describes the pathogenesis and progression of cartilage degeneration as well as the dietary, lifestyle and pharmacological management of osteoarthritis. Recent pharmacological developments allow the clinician not only to control clinical signs of the disease, but also to slow the progression of cartilage degeneration.
骨关节炎或退行性关节病是一种以关节软骨退变为特征的病症，常伴有关节边缘表面新骨形成。骨关节炎在犬类中常见，可能起病缓慢，但也可能急性发作。骨关节炎可以是关节软骨的原发性疾病，但更多是继发于关节的异常应力。本文描述了软骨退变的发病机制和进展以及骨关节炎的饮食、生活方式和药物治疗。近期的药物进展使临床医生不仅能够控制该病的临床症状，还能减缓软骨退变的进程。
