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输精管复通术失败:再次尝试显微手术是否值得?

Failed vasectomy reversal: is a further attempt worthwhile using microsurgery?

作者信息

Fox M

机构信息

Claremont Hospital, Sheffield, UK.

出版信息

Eur Urol. 1997;31(4):436-40. doi: 10.1159/000474503.

Abstract

OBJECTIVES

Following surgery for vasectomy reversal there is a substantial failure rate in achieving fertility. Obstruction at the anastomotic site is the cause in the majority of cases. Further exploration to reconstruct the anastomosis using no magnification or a magnifying loupe can be difficult and even impossible, and can result in further failure, especially if the convoluted part of the vas had been involved. The outcome of revision by a microscopic technique of vasovasostomy was thus investigated.

METHODS

A meticulous microsurgical technique employing a 2-layer interrupted suture, end-to-end anastomosis with 10/0 nylon, was used to establish continuity of the lumen.

RESULTS

Sperm in the ejaculate was achieved in 64% of 22 patients operated on after previous failure. Fertility rate after a mean follow-up of 23 months (range 8 months to 6 years) demonstrated by pregnancy in their partners has occurred so far in 27%. Length of the obstructive period was related to the outcome as well as the presence or absence of sperm at operation, but neither of these indicators or the presence of antisperm antibodies comprised a bar to eventual success.

CONCLUSION

Microsurgical vasovasostomy after previous failure provides the patient with further reasonable hope of success in becoming fertile, but microsurgical skills are required.

摘要

目的

输精管复通手术后,实现生育的失败率很高。大多数情况下,吻合部位的梗阻是导致失败的原因。在不使用放大设备或仅使用放大 loupe 的情况下进一步探索重建吻合术可能很困难甚至无法进行,并且可能导致进一步失败,尤其是当输精管的盘绕部分也受到影响时。因此,研究了采用显微技术进行输精管吻合术修复的结果。

方法

采用精细的显微外科技术,使用 10/0 尼龙线进行两层间断缝合、端端吻合,以建立管腔的连续性。

结果

在先前手术失败后接受手术的 22 例患者中,64% 的患者精液中出现了精子。在平均随访 23 个月(范围为 8 个月至 6 年)后,其伴侣怀孕显示的生育率目前为 27%。梗阻期的长短与结果以及手术时精子的有无有关,但这些指标中的任何一个或抗精子抗体的存在都不是最终成功的障碍。

结论

先前失败后进行显微外科输精管吻合术为患者提供了进一步合理的成功受孕希望,但需要显微外科技术。

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