Oner A, Demircin G, Ipekçioğlu H, Bülbül M, Ecin N
Department of Nephrology, Dr. Sami Ulus Children's Hospital, Ankara, Turkey.
Eur Urol. 1997;31(4):453-8. doi: 10.1159/000474506.
To evaluate the clinical and etiological characteristics of childhood urolithiasis in Turkey.
Ninety-two children with urolithiasis were studied retrospectively according to clinical patterns and etiological factors between January 1990 and January 1995.
The age range of the patients was from 2 months to 14 years (mean age 6.9 years), and there was a male/female ratio of 1.6. The onset of the disease was earlier in boys than in girls. The most striking features were the initial admission of 14 (15.2%) children after the development of chronic renal failure and that most of them (64.3%) had infection stones. The stones were localized in the upper urinary system in 68.5% of the patients; bladder stones were rare (10.9%). The recurrence rate at presentation was 15.2% in all patients. As etiological factors, an anatomical defect was found in 30.4% of the patients, infections in 31.5%, and metabolic disorders in 26.1%; 11 (12.0%) of them were classified as idiopathic. The earliest presentation was seen with metabolic and infection stones and the highest recurrence rate (37.5%) in patients with metabolic stones.
Childhood urolithiasis is a serious problem in Turkey. In order to prevent the development of end-stage renal failure and to improve the patients' quality of life, more efforts should be made with respect to early diagnosis and management of renal stones and urinary tract infections.
评估土耳其儿童尿路结石的临床及病因学特征。
回顾性研究1990年1月至1995年1月间92例尿路结石患儿的临床症状及病因。
患者年龄范围为2个月至14岁（平均年龄6.9岁），男女比例为1.6。男孩发病早于女孩。最显著的特征是14例（15.2%）患儿在出现慢性肾衰竭后首次入院，且其中大多数（64.3%）患有感染性结石。68.5%的患者结石位于上尿路系统；膀胱结石少见（10.9%）。所有患者就诊时的复发率为15.2%。病因方面，30.4%的患者存在解剖缺陷，31.5%存在感染，26.1%存在代谢紊乱；11例（12.0%）为特发性。代谢性和感染性结石出现症状最早，代谢性结石患者复发率最高（37.5%）。
儿童尿路结石在土耳其是一个严重问题。为预防终末期肾衰竭的发生并改善患者生活质量，应在肾结石及尿路感染的早期诊断和管理方面做出更多努力。
