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安纳托利亚东南部小儿尿路结石的特征

Characteristics of pediatric urolithiasis in south-east Anatolia.

作者信息

Ece A, Ozdemir E, Gürkan F, Dokucu A I, Akdeniz O

机构信息

Dicle University Medical Faculty Department of Pediatrics, Diyarbakir, Turkey.

出版信息

Int J Urol. 2000 Sep;7(9):330-4. doi: 10.1046/j.1442-2042.2000.00207.x.

Abstract

BACKGROUND

Urolithiasis is endemic in Turkey and characteristics of urolithiasis vary in different regions of the world. The aim of the present study was to evaluate the etiological and clinical characteristics and course of pediatric urolithiasis in south-east Turkey.

METHODS

The study population consisted of 81 children (52 girls) with urolithiasis at a mean age of 6.2 +/- 4.2 years who were followed up for 1-32 months.

RESULTS

Metabolic disorders, anatomical defects and infection stones were found to be the etiological factor in 34.6, 29.6 and 22.2% of patients, respectively, while 13.6% of patients were considered idiopathic. Of all patients, 28.4% were admitted with acute renal failure (ARF) and 72.8% had urinary tract infection. Recurrence was seen in 19.8% of patients at presentation. The localization of the stone was found to be in the upper urinary tract, the lower urinary tract or both in 65.4, 14.8% and 17.3% of patients, respectively. Patients with multiple and bilateral stones had a higher risk for ARF than the others. The risk for chronic renal failure was significantly higher in children with multiple, bilateral or recurrent stones and with ARF at presentation.

CONCLUSIONS

Early diagnosis and management of renal stones and urinary tract infections is necessary to prevent the development of ARF or chronic renal failure and to improve the quality of a patient's life.

摘要

背景

尿路结石在土耳其呈地方性流行,且世界各地尿路结石的特征各不相同。本研究的目的是评估土耳其东南部小儿尿路结石的病因、临床特征及病程。

方法

研究对象为81例尿路结石患儿(52例女孩),平均年龄6.2±4.2岁,随访1 - 32个月。

结果

代谢紊乱、解剖缺陷和感染性结石分别是34.6%、29.6%和22.2%患者的病因,而13.6%的患者病因不明。所有患者中,28.4%因急性肾衰竭(ARF)入院,72.8%有尿路感染。19.8%的患者初诊时即出现复发。结石位于上尿路、下尿路或上下尿路均有的患者分别占65.4%、14.8%和17.3%。多发和双侧结石患者发生ARF的风险高于其他患者。初诊时患有多发、双侧或复发性结石以及ARF的儿童发生慢性肾衰竭的风险显著更高。

结论

早期诊断和处理肾结石及尿路感染对于预防ARF或慢性肾衰竭的发生以及提高患者生活质量很有必要。

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