Vasankari T J, Kujala U M, Rusko H, Sarna S, Ahotupa M
Paavo Nurmi Center, Sports Medical Research Unit, Turku, Finland.
Eur J Appl Physiol Occup Physiol. 1997;75(5):396-9. doi: 10.1007/s004210050178.
We investigated the effect of training and racing at moderate altitude (MA) on oxidative stress by assessment of serum diene conjugation (DC) and serum antioxidant potential (TRAP). Nine male top level skiers were studied during a national race (20-30 km) at sea level (SL). Thereafter, the athletes trained for 2 weeks at MA, after which they participated in a 20-30 km race at MA. Venous blood samples were taken before and after the race. The DC, indicating early events of lipid peroxidation, did not change during the race at SL (16 850 vs 15 900 delta Absorbance.l-1) or at MA (19 870 vs. 20 630 delta Abs.l-1). At MA serum DC was higher than at SL both before (25%) and after (30%) the race, the postrace difference being statistically significant (P < 0.05). The TRAP increased during the race at MA (from 1387 to 1943 mumol.l-1, P = 0.016), but not at SL (1713 vs 1582 mumol.l-1). These observations would suggest that the level of oxidative stress might be greater during living, training and racing at MA (higher DC levels). Increased TRAP during the race at MA may indicate that the physiological adaptation to extreme acute oxidative stress was altered. The physiological significance of this observation remains to be investigated.
我们通过评估血清二烯共轭（DC）和血清抗氧化能力（TRAP），研究了在中等海拔（MA）进行训练和比赛对氧化应激的影响。对9名男性顶级滑雪运动员在海平面（SL）进行的一场全国性比赛（20 - 30公里）期间进行了研究。此后，运动员在中等海拔进行了2周的训练，之后他们在中等海拔参加了一场20 - 30公里的比赛。在比赛前后采集静脉血样。DC表明脂质过氧化的早期事件，在海平面比赛期间（16850对15900吸光度变化值·升⁻¹）或在中等海拔比赛期间（19870对20630吸光度变化值·升⁻¹）均未改变。在中等海拔，比赛前血清DC高于海平面（高25%），比赛后也高于海平面（高30%），赛后差异具有统计学意义（P < 0.05）。在中等海拔比赛期间TRAP升高（从1387升至1943微摩尔·升⁻¹，P = 0.016），但在海平面比赛期间未升高（1713对1582微摩尔·升⁻¹）。这些观察结果表明，在中等海拔生活、训练和比赛期间氧化应激水平可能更高（DC水平更高）。在中等海拔比赛期间TRAP升高可能表明对极端急性氧化应激的生理适应发生了改变。这一观察结果的生理意义仍有待研究。
